An enormous amount of research effort has been devoted to biomarker discovery and
validation. With the completion of the human genome, proteomics is now playing an …

Hepatocellular carcinoma (HCC) or hepatoma is malignant cancer that starts from the main
liver cells. Although various classical methods have been used for patients with HCC …

Introduction The importance of biomarkers for pharmaceutical drug development and clinical
diagnostics is more significant than ever in the current shift toward personalized medicine …

Introduction: Numerous diseases are caused by changes in post-translational modifications
(PTMs). Therefore, the number of clinical proteomics studies that include the analysis of …

In an era when the rising global population has ever-increasing demands, plant resources
form an integral part of the basic needs. Plant diseases ruin the harvest and also the hopes …

Rapid and sensitive detection of clinical biomolecules in a multiplexed fashion is of great
importance for accurate diagnosis of diseases. Mass spectrometric (MS) approaches are …

Highlights•Describes the challenges in intact protein bioanalysis by LC-MS•Describes
approaches to reduce the width of the charge-state envelope upon electrospray ionization …

Oral cavity cancer is a common cancer type that presents an increasingly serious global
problem. Oral squamous cell carcinoma (OSCC) accounts for> 90% oral cancer cases. No …

Background: The current study aimed to investigate the effects of TUG1 on the migration and
invasion of hepatoma cells. Materials and Methods: The expressions of TUG1, miR-137, and …

Protein mass spectrometry (MS) is an indispensable tool to detect molecular signatures that
can be associated with cellular dysregulation and disease. Despite its huge success in the …