Head and neck squamous cell carcinoma (HNSCC), an aggressive malignancy, is
characterized by high morbidity and low survival rates with limited therapeutic options …

Oral cancer is one of the most leading cancer responsible for significant morbidity and
mortality. The sirtuins (SIRTs) are a family of class III histone deacetylases and are known to …

Abstract Tumour Necrosis Factor-α (TNF-α) plays a vital role in apoptosis and cancer. Till
date, there is no existing biosensor for detecting TNF-α in cancer patients serum samples …

Objective: Alcohol affects many human systems and is involved in the pathogenesis of other
diseases. Particular attention must be paid to alcohol consumption among young people. It …

Alcohol is a legal and yet detrimental psychoactive substance, capable of establishing
addiction and impacting the physical, mental, social, and economic health of people. Alcohol …

Aberrant expression of the programmed cell death protein ligand 1 (PD-L1) constitutes one
of the main immune evasion mechanisms of cancer cells. The approval of drugs against the …

Simple Summary Malignant phenotypes of head and neck squamous cell carcinomas
(HNSCCs) are regulated by the pro-and anti-tumoral activities of immune modulatory …

The immune system plays a significant role in the development, invasion, progression, and
metastasis of head and neck cancer. Over the last decade, the emergence of …

Evidence shows that there is a synergistic, bidirectional association between cancer and
aging with many shared traits. Age itself is a risk factor for the onset of most cancers, while …

Oropharyngeal squamous cell carcinoma (OPSCC) is an uncommon malignancy worldwide.
Remarkably, the rising incidence of OPSCC has been observed in many developed …