miRNAs as Cornerstones in Chronic Lymphocytic Leukemia Pathogenesis and Therapeutic Resistance–An emphasis on the interaction of signaling pathways

AS Doghish, AI Abulsoud, SS Elshaer… - … -Research and Practice, 2023 - Elsevier
Chronic lymphocytic leukemia (CLL) accounts for the vast majority of cases of leukemia.
Patients of advanced age are more likely to develop the condition, which has a highly varied …

The dark side of stemness–the role of hematopoietic stem cells in development of blood malignancies

J Filipek-Gorzała, P Kwiecińska, A Szade… - Frontiers in …, 2024 - frontiersin.org
Hematopoietic stem cells (HSCs) produce all blood cells throughout the life of the organism.
However, the high self-renewal and longevity of HSCs predispose them to accumulate …

Analysis of primary chronic lymphocytic leukemia cells' signaling pathways

J Skelin, M Matulić, L Milković, D Heckel, J Skoko… - Biomedicines, 2024 - mdpi.com
Chronic lymphocytic leukemia (CLL) is a lymphoproliferative disorder characterized by a
specific expansion of mature B-cell clones. We hypothesized that the disease has a …

[HTML][HTML] Autoimmune cytopenias in chronic lymphocytic leukemia

MS Haider, SA Khan, S Shahid - Pakistan Journal of Medical …, 2019 - ncbi.nlm.nih.gov
Objective: To determine the frequency of autoimmune cytopenias in chronic lymphocytic
leukemia. Methods: This cross sectional study was carried out at Department of Hematology …

[Retracted] Analysis of Data on Fludarabine, Cyclophosphamide, and Rituximab Chemoimmunotherapy for Chronic Lymphocytic Leukemia Shows High Patient …

X Xu, Y Zhao, H Ye, Y Qi, W Xu, Y Ling… - … Methods in Medicine, 2022 - Wiley Online Library
Object. In this study, bioinformatics analysis of differentially expressed genes (DEGs) and
signaling pathway activities in different progression stages of chronic lymphocytic leukemia …

Evaluation of prognostic variables in chronic lymphocytic leukemia and association with disease stage

HRM Attia, MH Ibrahim, A El‑Aziz… - Molecular and …, 2021 - spandidos-publications.com
The aim of the present study was to investigate different biological prognostic markers to
identify high‑risk patients with chronic lymphocytic leukemia (CLL) with a higher tumor …

[HTML][HTML] 低剂量FCR 方案治疗老年非高危慢性淋巴细胞白血病患者的疗效观察

林莺, 张荣东, 陈仁利 - 实用肿瘤杂志, 2020 - html.rhhz.net
目的探讨低剂量FCR (氟达拉滨+ 环磷酰胺+ 利妥昔单抗) 方案治疗老年慢性淋巴细胞白血病(
chroniclymphocytic leukemia, CLL) 患者的价值. 方法回顾性分析86 例老年CLL …

Promising Role of CD200 Expression in Diagnosis and Prognosis of Chronic Lymphocytic Leukemia: A Review

M Zahedi, SSK Khorasani, A Nasirzadeh… - International Journal of …, 2019 - intjmi.com
One of the most common leukemia in the world is chronic lymphocytic leukemia (CLL). CLL,
as an incurable malignant disorder of B-lymphocytes. CD200, formerly known as OX-2, is a …

Evaluation of the frequency of benign reactive lymphocytosis and lymphoproliferative disorders by flow cytometry in patients with persistent lymphocytosis in …

BM Jazi, P Nematollahy, N Maktoobian - Journal of Renal …, 2024 - jrenendo.com
Introduction: Lymphocytosis is characterized by an elevation in the absolute lymphocyte
count (ALC) to over 4000 lymphocytes per microliter among adults. In lymphocytosis, the …

[PDF][PDF] Smjernice za liječenje kronične limfocitne leukemije, studeni 2021

V Pejša, B Jakšić, S Ostojić Kolonić, SB Kinda, B Coha… - Bilten Krohema - krohem.hr
U veljači 2020. dopunjene su nacionalne smjernice za liječenje kronične limfocitne
leukemije (KLL) nakon odličnih rezultata kliničke studije CLL141. Prihvaćena je …