Viruses and multiple sclerosis

J Oskari Virtanen, S Jacobson - CNS & Neurological Disorders …, 2012 - ingentaconnect.com
Multiple sclerosis (MS) is a heterogeneous disease that develops as an interplay between
the immune system and environmental stimuli in genetically susceptible individuals. There is …

Human herpesviruses 6A and 6B in brain diseases: association versus causation

AL Komaroff, PE Pellett, S Jacobson - Clinical microbiology …, 2020 - Am Soc Microbiol
SUMMARY Human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B),
collectively termed HHV-6A/B, are neurotropic viruses that permanently infect most humans …

Increased serological response against human herpesvirus 6A is associated with risk for multiple sclerosis

E Engdahl, R Gustafsson, J Huang, M Biström… - Frontiers in …, 2019 - frontiersin.org
Human herpesvirus (HHV)-6A or HHV-6B involvement in multiple sclerosis (MS) etiology
has remained controversial mainly due to the lack of serological methods that can …

Evidence linking HHV-6 with multiple sclerosis: an update

EC Leibovitch, S Jacobson - Current opinion in virology, 2014 - Elsevier
Highlights•Additional observations of HHV6-specific B and T cell reactivity in MS
CSF.•Evidence of correlations between HHV6 status, polymorphisms and response to …

Relationship of human herpes virus 6 and multiple sclerosis: a systematic review and meta‐analysis

A Pormohammad, T Azimi, F Falah… - Journal of cellular …, 2018 - Wiley Online Library
Infection with human herpes viruses has been suggested to contribute to multiple sclerosis
(MS), while interaction between human herpes 6 (HHV6) and MS remain unclear yet. Here …

The probable infectious origin of multiple sclerosis

RL Landry, ME Embers - NeuroSci, 2023 - mdpi.com
Multiple sclerosis (MS) is an immune inflammatory disease that causes demyelination of the
white matter of the central nervous system. It is generally accepted that the etiology of MS is …

Anti-HHV-6 IgG titer significantly predicts subsequent relapse risk in multiple sclerosis

S Simpson Jr, B Taylor, DE Dwyer… - Multiple Sclerosis …, 2012 - journals.sagepub.com
Background: Some of the strongest associations with MS onset are for human
herpesviruses, particularly Epstein–Barr virus (EBV) and human herpesvirus 6 (HHV-6) …

Human herpesvirus 6 infection as a trigger of multiple sclerosis: an update of recent literature

KI Voumvourakis, PC Fragkou, DK Kitsos, K Foska… - BMC neurology, 2022 - Springer
Background This is an update on the existing evidence regarding a relationship between
infection with human herpesvirus 6 (HHV-6) and multiple sclerosis (MS) in order to …

Infectious agents and different course of multiple sclerosis: a systematic review

A Saberi, S Akhondzadeh, S Kazemi - Acta Neurologica Belgica, 2018 - Springer
Multiple sclerosis (MS) causes demyelination of white matter of central nervous system and
neuro-degeneration due to inflammation. Different types of MS, as well as disease …

Human herpesvirus 6 and 7 reactivation and disease activity in multiple sclerosis

Z Nora-Krukle, S Chapenko, I Logina, A Millers… - Medicina, 2011 - dspace.rsu.lv
Recent studies have focused on the associations between human herpesvirus 6 (HHV-6)
and human herpesvirus 7 (HHV-7), and multiple sclerosis (MS). The aim of this study was to …