Histone posttranslational modifications (HPTMs) are crucial epigenetic mechanisms
regulating various biological events. Different types of HPTMs characterize and shape …

Post-translational modifications (PTM) are covalent modifications of proteins or peptides
caused by proteolytic cleavage or the attachment of moieties to one or more amino acids …

Objective We previously reported that β-oxidation enzymes are present in the nucleus in
close proximity to transcriptionally active promoters. Thus, we hypothesized that the fatty …

Metastatic cancer is a major cause of cancer-related mortality; however, the complex
regulation process remains to be further elucidated. A large amount of preliminary …

Histone post-translational modifications (HPTMs), as one of the core mechanisms of
epigenetic regulation, are garnering increasing attention due to their close association with …

Protein posttranslational modification (PTM) is a biochemical mechanism benefitting cellular
adaptation to dynamic intracellular and environmental conditions. Recently, several …

Transcriptional repressor B cell lymphoma 6 (Bcl6) is a major transcription factor involved in
Tfh cell differentiation and germinal center response, which is regulated by a variety of …

Stem cells represent the regenerative capacity of our bodies; hence, it is essential for these
cells to interact with the intrinsic and extrinsic environments, including nutritional …

Posttranslational modification dramatically enhances protein complexity, but the function
and precise mechanism of novel lysine acylation modifications remain unknown …

Background and purpose: Increase in ATP-dependent Citrate Lyase (ACLY) is observed in
individuals with nonalcoholic fatty liver disease (NAFLD). One of the compounds considered …