Unravelling the Threat of Contamination in Elite Sports: Exploring Diverse Sources Impacting Adverse Analytical Findings and the Risk of Inadvertent exposure to …

ABM Merlo, L Lobigs, T Piper, C Champod… - Forensic science …, 2024 - Elsevier
In recent years, increasing concerns have emerged regarding athletes being exposed to
various sources of contamination that could result in an adverse analytical finding (AAF) …

The pharmacokinetics of letrozole and its effect on gonadotropins in anestrous ewes

MB Kivrak, O Corum, H Alkan, O Atik, I Aydin, K Uney - Theriogenology, 2021 - Elsevier
The aim of this study was to determine the pharmacokinetics of letrozole and its effect on
FSH and LH concentrations after single (IV, IM, SC) and repeated IV doses in anestrous …

Expression and characterization of the cyp19a gene and its responses to estradiol/letrozole exposure in Chinese soft‐shelled turtle (Pelodiscus sinensis)

HW Liang, Y Meng, LH Cao, X Li… - Molecular reproduction …, 2019 - Wiley Online Library
Abstract Cytochrome P450 aromatase (CYP19) catalyzes the conversion of androgens to
estrogens and is critical in sex differentiation. CYP19 exists as the ovarian type and brain …

Novel Naphthoquinones as Potent Aromatase Inhibitors: Synthesis, Anticancer, and In silico studies

R Leechaisit, P Mahalapbutr, U Suriya… - Journal of Molecular …, 2024 - Elsevier
A set of 26 naphthoquinone derivatives (3-28) were synthesized by nucleophilic substitution
or Michael addition of various amines with 1, 4-naphthoquinones and were investigated for …

Contributing factors related to abnormal uterine bleeding in perimenopausal women: a case–control study

Y Tian, B Bai, L Wang, Z Zhou, J Tang - Journal of Health, Population and …, 2024 - Springer
Abnormal uterine bleeding (AUB) during the menopausal transition results in reproductive
endocrine disorders and both physiological and pathological changes, substantially …

Cholesterol-cyclodextrin complex as a replacement for egg yolk in bull semen extender: Sperm characteristics post-thawing and in vivo fertility

SX Yang, GP Adams, EM Zwiefelhofer… - Animal Reproduction …, 2021 - Elsevier
Egg yolk, a major semen extender constituent, lacks a defined composition, therefore, there
are biosecurity concerns with use of egg yolk. Cryopreservation of bull semen without …

Development of a letrozole-based synchronization protocol for fixed-time artificial insemination in beef cattle

EM Zwiefelhofer, W Lillico, GP Adams - Animal Reproduction Science, 2022 - Elsevier
Experiments were done to determine ovulation synchrony following a 4-day letrozole
treatment (Exp 1), compare the efficacy of a letrozole-based protocol with other commonly …

Research and development of a silicone letrozole-releasing device to control reproduction in cattle

EM Zwiefelhofer, BM Davis, GP Adams - Theriogenology, 2020 - Elsevier
Two experiments were conducted to test the effectiveness of a silicone matrix as an
intravaginal drug delivery device for letrozole, an aromatase inhibitor used for …

Effect of a non-steroidal aromatase inhibitor on ovarian function and synchronicity of estrus in ewes at subtropics

AD MA - Journal of Applied Veterinary Sciences, 2020 - journals.ekb.eg
Effects of non-steroidal aromatase inhibitor letrozole on ovarian function in ewe were
investigated through testing the hypothesis that letrozole will arrest the growth of dominant …

An attempt to potentiate the ovarian superstimulatory response in cattle by co-treatment with an aromatase inhibitor

EM Zwiefelhofer, RJ Mapletoft, GP Adams - Theriogenology, 2020 - Elsevier
Letrozole is used for the treatment of subfertility in women undergoing ovarian
superstimulation, but the mechanism of action has not been investigated critically. The …