[HTML][HTML] Lyme borreliosis

AC Steere, F Strle, GP Wormser, LT Hu… - Nature reviews Disease …, 2016 - nature.com
Lyme borreliosis is a tick-borne disease that predominantly occurs in temperate regions of
the northern hemisphere and is primarily caused by the bacterium Borrelia burgdorferi in …

[HTML][HTML] Recent progress in Lyme disease and remaining challenges

JR Bobe, BL Jutras, EJ Horn, ME Embers… - Frontiers in …, 2021 - frontiersin.org
Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in
the United States with an estimated 476,000 cases per year. While historically, the long-term …

Clinical practice guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology …

PM Lantos, J Rumbaugh… - Clinical Infectious …, 2021 - academic.oup.com
This evidence-based clinical practice guideline for the prevention, diagnosis, and treatment
of Lyme disease was developed by a multidisciplinary panel representing the Infectious …

Lyme disease in humans

JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

Lyme arthritis: linking infection, inflammation and autoimmunity

RB Lochhead, K Strle, SL Arvikar, JJ Weis… - Nature Reviews …, 2021 - nature.com
Infectious agents can trigger autoimmune responses in a number of chronic inflammatory
diseases. Lyme arthritis, which is caused by the tick-transmitted spirochaete Borrelia …

[HTML][HTML] Autoimmunity to synovial extracellular matrix proteins in patients with postinfectious Lyme arthritis

K Kanjana, K Strle, RB Lochhead… - The Journal of …, 2023 - Am Soc Clin Investig
BACKGROUND Autoimmune diseases often have strong genetic associations with specific
HLA-DR alleles. The synovial lesion in chronic inflammatory forms of arthritis shows marked …

[HTML][HTML] Post-treatment Lyme disease as a model for persistent symptoms in Lyme disease

AW Rebman, JN Aucott - Frontiers in medicine, 2020 - frontiersin.org
It has long been observed in clinical practice that a subset of patients with Lyme disease
report a constellation of symptoms such as fatigue, cognitive difficulties, and musculoskeletal …

Diagnosis and treatment of Lyme arthritis

SL Arvikar, AC Steere - Infectious Disease Clinics, 2015 - id.theclinics.com
Lyme arthritis was recognized originally because of an outbreak of monoarticular and
oligoarticular arthritis in children in Lyme, Connecticut, in the 1970s. 1 It then became …

Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis

BL Jutras, RB Lochhead, ZA Kloos… - Proceedings of the …, 2019 - National Acad Sciences
Lyme disease is a multisystem disorder caused by the spirochete Borrelia burgdorferi. A
common late-stage complication of this disease is oligoarticular arthritis, often involving the …

Lyme disease: a rigorous review of diagnostic criteria and treatment

AT Borchers, CL Keen, AC Huntley… - Journal of autoimmunity, 2015 - Elsevier
Lyme disease was originally identified in Lyme, Connecticut, based upon an unusual cluster
of what appeared to be patients with juvenile rheumatoid arthritis. It was subsequently …