Conjugates of porphyrinoid-based photosensitizers with cytotoxic drugs: current progress and future directions toward selective photodynamic therapy

VF Otvagin, NS Kuzmina, ES Kudriashova… - Journal of medicinal …, 2022 - ACS Publications
Photodynamic therapy (PDT) is a treatment modality where light-mediated activation of
photosensitizers in a patient's body leads to the generation of cytotoxic reactive oxygen …

[HTML][HTML] EGFR-targeted photodynamic therapy

L Ulfo, PE Costantini, M Di Giosia, A Danielli… - Pharmaceutics, 2022 - mdpi.com
The epidermal growth factor receptor (EGFR) plays a pivotal role in the proliferation and
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …

[HTML][HTML] Macroheterocyclic compounds a key building block in new functional materials and molecular devices

OI Koifman, TA Ageeva, IP Beletskaya… - …, 2020 - cyberleninka.ru
The review discusses the latest advances in the directed synthesis and application of
macroheterocyclic compounds in science, engineering and technology, viz. as catalysts for …

Photosensitizer antibody–drug conjugates: past, present, and future

J Sandland, RW Boyle - Bioconjugate chemistry, 2019 - ACS Publications
This Review aims to highlight key aspects of tetrapyrrole-based antibody–drug conjugates
(ADCs) and significant developments in the field since 2010. Many new conjugation …

Water-soluble chlorin/arylaminoquinazoline conjugate for photodynamic and targeted therapy

VF Otvagin, NS Kuzmina, LV Krylova… - Journal of Medicinal …, 2019 - ACS Publications
A new water-soluble conjugate, consisting of a chlorin-e 6 photosensitizer part, a 4-
arylaminoquinazoline moiety with affinity to epidermal growth factor receptors, and a …

[HTML][HTML] Main Strategies for the Synthesis of meso-Arylporphyrins

OI Koifman, TA Ageeva - Russian Journal of Organic Chemistry, 2022 - Springer
Abstract meso-Arylporphyrins as most accessible tetrapyrrole macroheterocycles have
always been the focus of attention from researchers concerned with practically useful …

[HTML][HTML] A biotin receptor-targeted silicon (IV) phthalocyanine for in vivo tumor imaging and photodynamic therapy

K Li, W Dong, Q Liu, G Lv, M Xie, X Sun, L Qiu… - … of Photochemistry and …, 2019 - Elsevier
Phthalocyanines (Pcs) are a kind of potential photosensitizers for fluorescence imaging and
photodynamic therapy (PDT). However, the clinical application of Pcs is suffered from their …

Development of novel porphyrin/combretastatin A-4 conjugates for bimodal chemo and photodynamic therapy: Synthesis, photophysical and TDDFT computational …

NS Kuzmina, VF Otvagin, AA Maleev… - … of Photochemistry and …, 2022 - Elsevier
Anticancer photodynamic therapy (PDT) in recent years has gained attention among
therapists due to its low systemic toxicity and non-invasive nature. Today, one of the big …

Synthesis, acid-base interactions, and photostability of copper(ii) tetrakis(3,5-di-tert-butylbenzoyloxy)phthalocyanine

AS Malyasova, EA Kostrova, IG Abramov… - Russian Chemical …, 2021 - Springer
Dicyanophenyl 3, 5-di-tert-butylbenzoate was synthesized for the first time. Copper tetrakis
(3, 5-di-tert-butylbenzoyloxy) phthalocyaninate was obtained also for the first time from this …

Photodynamic antitumor activity of Gallium (III) and Phosphorus (V) complexes of trimethoxyl A2B triaryl corrole

W Yang, G Yang, MY Li, ZY Liu, YH Liao, HY Liu - Bioorganic Chemistry, 2022 - Elsevier
Two new trimethoxyl A 2 B triaryl corroles 10-(2, 4, 6-trimethoxyphenyl)-5, 15-bis
(pentafluorophenyl)-corrole (1) and 10-(3, 4, 5-trimethoxyphenyl)-5, 15-bis …