The changing epidemiology of invasive fungal infections

DA Enoch, H Yang, SH Aliyu, C Micallef - Human fungal pathogen …, 2017 - Springer
Invasive fungal infections (IFI) are an emerging problem worldwide with invasive candidiasis
and candidemia responsible for the majority of cases. This is predominantly driven by the …

Antifungal drug resistance among Candida species: mechanisms and clinical impact

M Sanguinetti, B Posteraro, C Lass‐Flörl - Mycoses, 2015 - Wiley Online Library
The epidemiology of Candida infections has changed in recent years. Although Candida
albicans is still the main cause of invasive candidiasis in most clinical settings, a substantial …

T2 magnetic resonance assay for the rapid diagnosis of candidemia in whole blood: a clinical trial

E Mylonakis, CJ Clancy… - Clinical Infectious …, 2015 - academic.oup.com
Background. Microbiologic cultures, the current gold standard diagnostic method for
invasive Candida infections, have low specificity and take up to 2–5 days to grow. We …

Epidemiology and outcomes of candidemia in 3648 patients: data from the Prospective Antifungal Therapy (PATH Alliance®) registry, 2004–2008

M Pfaller, D Neofytos, D Diekema, N Azie… - … and infectious disease, 2012 - Elsevier
This analysis describes the epidemiology and outcomes of candidemia in patients enrolled
in the Prospective Antifungal Therapy Alliance (PATH Alliance®) registry from 2004 to 2008 …

Changes in incidence and antifungal drug resistance in candidemia: results from population-based laboratory surveillance in Atlanta and Baltimore, 2008–2011

AA Cleveland, MM Farley, LH Harrison… - Clinical infectious …, 2012 - academic.oup.com
Background. Candidemia is common and associated with high morbidity and mortality;
changes in population-based incidence rates have not been reported. Methods. We …

Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus

SS Gonçalves, ACR Souza, A Chowdhary, JF Meis… - Mycoses, 2016 - Wiley Online Library
The significant increase in the use of antifungal agents, both for the treatment of candidiasis
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …

Recent exposure to caspofungin or fluconazole influences the epidemiology of candidemia: a prospective multicenter study involving 2,441 patients

O Lortholary, M Desnos-Ollivier, K Sitbon… - Antimicrobial agents …, 2011 - Am Soc Microbiol
ABSTRACT A prospective multicenter surveillance program on yeast bloodstream infections
was implemented in the Paris, France, area without restrictions on ward of hospitalization …

[HTML][HTML] Prognostic factors and historical trends in the epidemiology of candidemia in critically ill patients: an analysis of five multicenter studies sequentially conducted …

AL Colombo, T Guimarães, T Sukienik… - Intensive care …, 2014 - Springer
Purpose To describe temporal trends in the epidemiology, clinical management and
outcome of candidemia in intensive care unit (ICU) patients. Methods This study was a …

A research agenda on the management of intra-abdominal candidiasis: results from a consensus of multinational experts

M Bassetti, M Marchetti, A Chakrabarti, S Colizza… - Intensive care …, 2013 - Springer
Introduction intra-abdominal candidiasis (IAC) may include Candida involvement of
peritoneum or intra-abdominal abscess and is burdened by high morbidity and mortality …

Antibiotic exposure as a risk factor for fluconazole-resistant Candida bloodstream infection

R Ben-Ami, K Olshtain-Pops, M Krieger… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Recent exposure to azoles is an important risk factor for infection with fluconazole-resistant
Candida spp., but little is known about the role of antibacterial drug exposure in the …