Mass spectrometry (MS) has become one of the key technologies of structural biology. In this
review, the contributions of chemical cross-linking combined with mass spectrometry (XL …

Structural mass spectrometry (MS) is gaining increasing importance for deriving valuable
three‐dimensional structural information on proteins and protein complexes, and it …

(MS) and MS-driven proteomics have continued to develop as the premier tools for
characterizing proteome composition, structure, and function. 2 The new era of proteomics …

Protein-protein interactions govern most cellular pathways and processes, and multiple
technologies have emerged to systematically map them. Assessing the error of interaction …

Observing the structures of proteins within the cell and tracking structural changes under
different cellular conditions are the ultimate challenges for structural biology. This, however …

Crosslinking mass spectrometry has developed into a robust technique that is increasingly
used to investigate the interactomes of organelles and cells. However, the incomplete and …

Cross-linking mass spectrometry is becoming increasingly popular, and current advances
are widening the applicability of the technique so that it can be utilized by nonspecialist …

Introduction: Protein cross-links are common in biological systems and are generated both
deliberately as a part of normal metabolism and also accidently as a result of exposure to …

We compared the five different ways of fragmentation available on a tribrid mass
spectrometer and optimized their collision energies with regard to optimal sequence …

For decades, chemical cross-linking of proteins has been an established method to study
protein interaction partners. The chemical cross-linking approach has recently been revived …