Nuclear physics in particle therapy: a review

M Durante, H Paganetti - Reports on Progress in Physics, 2016 - iopscience.iop.org
Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

Prompt-gamma monitoring in hadrontherapy: A review

J Krimmer, D Dauvergne, JM Létang, É Testa - Nuclear Instruments and …, 2018 - Elsevier
Secondary radiation emission induced by nuclear reactions is correlated to the path of ions
in matter. Therefore, such penetrating radiation can be used for in vivo control of …

In vivo range verification in particle therapy

K Parodi, JC Polf - Medical physics, 2018 - Wiley Online Library
Exploitation of the full potential offered by ion beams in clinical practice is still hampered by
several sources of treatment uncertainties, particularly related to the limitations of our ability …

Prompt gamma imaging with a slit camera for real-time range control in proton therapy

J Smeets, F Roellinghoff, D Prieels… - Physics in Medicine …, 2012 - iopscience.iop.org
Treatments delivered by proton therapy are affected by uncertainties on the range of the
beam within the patient, requiring medical physicists to add safety margins on the …

Range verification methods in particle therapy: underlying physics and Monte Carlo modeling

AC Kraan - Frontiers in oncology, 2015 - frontiersin.org
Hadron therapy allows for highly conformal dose distributions and better sparing of organs-
at-risk, thanks to the characteristic dose deposition as function of depth. However, the quality …

Imaging of prompt gamma rays emitted during delivery of clinical proton beams with a Compton camera: feasibility studies for range verification

JC Polf, S Avery, DS Mackin… - Physics in Medicine & …, 2015 - iopscience.iop.org
The purpose of this paper is to evaluate the ability of a prototype Compton camera (CC) to
measure prompt gamma rays (PG) emitted during delivery of clinical proton pencil beams for …

Development of a Compton camera for medical applications based on silicon strip and scintillation detectors

J Krimmer, JL Ley, C Abellan, JP Cachemiche… - Nuclear Instruments and …, 2015 - Elsevier
A Compton camera is being developed for the purpose of ion-range monitoring during
hadrontherapy via the detection of prompt-gamma rays. The system consists of a scintillating …

Spectroscopic study of prompt-gamma emission for range verification in proton therapy

L Kelleter, A Wrońska, J Besuglow, A Konefał… - Physica Medica, 2017 - Elsevier
We present the results of an investigation of the prompt-gamma emission from an interaction
of a proton beam with phantom materials. Measurements were conducted with a novel setup …

Performance evaluation of MACACO: a multilayer Compton camera

E Muñoz, J Barrio, A Etxebeste… - Physics in Medicine …, 2017 - iopscience.iop.org
Compton imaging devices have been proposed and studied for a wide range of
applications. We have developed a Compton camera prototype which can be operated with …

A feasibility study of enhanced prompt gamma imaging for range verification in proton therapy using deep learning

Z Jiang, JC Polf, CA Barajas… - Physics in Medicine & …, 2023 - iopscience.iop.org
Background and objective. Range uncertainty is a major concern affecting the delivery
precision in proton therapy. The Compton camera (CC)-based prompt-gamma (PG) imaging …