Drug resistance is mainly responsible for cancer recurrence and poor prognosis. Epigenetic
regulation is a heritable change in gene expressions independent of nucleotide sequence …

The occurrence of cancer entails a series of genetic mutations that favor uncontrollable
tumor growth. It is believed that various factors collectively contribute to cancer, and there is …

Lysine-specific demethylase 5A (KDM5A, also named RBP2 or JARID1A) is a demethylase
that can remove methyl groups from histones H3K4me1/2/3. It is aberrantly expressed in …

Originally considered to act as a transcriptional co-factor, Pirin has recently been reported to
play a role in tumorigenesis and the malignant progression of many tumors. Here, we have …

Canine oral melanoma (COM) is a highly aggressive tumour associated with poor prognosis
due to metastasis and resistance to conventional anti-cancer therapies. As with human …

Many patients with esophageal squamous cell carcinoma (ESCC) are inoperable because
of old age or the advanced stage of the disease; thus radio-and chemotherapy are believed …