The endothelium exerts multiple actions involving regulation of vascular permeability and
tone, coagulation and fibrinolysis, inflammatory and immunological reactions and cell …

Kinins are proinflammatory peptides that mediate numerous vascular and pain responses to
tissue injury. Two pharmacologically distinct kinin receptor subtypes have been identified …

COVID-19 patients can present with pulmonary edema early in disease. We propose that
this is due to a local vascular problem because of activation of bradykinin 1 receptor (B1R) …

This study evaluated the anti-inflammatory properties of two sesquiterpenes isolated from
Cordia verbenacea's essential oil, α-humulene and (−)-trans-caryophyllene. Our results …

The cannabinoid type two receptors (CB2), an important component of the endocannabinoid
system, have recently emerged as neuromodulators and therapeutic targets for …

Cannabinoid receptor 2 (CB2) activation is suggested to trigger the peroxisome proliferator-
activated receptor-γ (PPARγ) pathway, and agonists of both receptors improve colitis …

Kinins, which are produced by the action of kallikrein enzymes, are blood-derived local-
acting peptides that have broad effects mediated by two related G-protein-coupled receptors …

The anti-inflammatory and anti-allergic effects of the essential oil of Cordia verbenacea
(Boraginaceae) and some of its active compounds were evaluated. Systemic treatment with …

Most striking observations in COVID-19 patients are the hints on pulmonary edema (also
seen on CT scans as ground glass opacities), dry cough, fluid restrictions to prevent more …

Kinins are a family of peptides implicated in several pathophysiological events. Most of their
effects are likely mediated by the activation of two G‐protein‐coupled receptors: B1 and B2 …