Exosomes are extracellular vesicles that are released by cells and circulate freely in body
fluids. Under physiological and pathological conditions, they serve as cargo for various …

Information processing within neuronal circuits relies on their proper development and a
balanced interplay between principal and local inhibitory interneurons within those circuits …

Spinal motor neurons (MNs) integrate sensory stimuli and brain commands to generate
movements. In vertebrates, the molecular identities of the cardinal MN types such as those …

The nervous system requires metabolites and oxygen supplied by the neurovascular
network, but this necessitates close apposition of neurons and endothelial cells. We find …

In the brain, microRNAs (miRNAs) are believed to play a role in orchestrating synaptic
plasticity at a higher level by acting as an additional mechanism of translational regulation …

Vascular cognitive impairment (VCI) due to chronic cerebral hypoperfusion (CCH), is the
second leading cause of dementia. Although synaptic impairment plays a critical role in VCI …

The assembly of the mammalian brain is orchestrated by temporally coordinated waves of
gene expression. Post-transcriptional regulation by microRNAs (miRNAs) is a key aspect of …

Generation of motor neurons (MNs) from human-induced pluripotent stem cells (hiPSCs)
overcomes the limited access to human brain tissues and provides an unprecedent …

MicroRNAs are non‐coding RNAs, approximately 22 nt in length, which serve to negatively
regulate gene expression through binding to complementary sequences in the 3 …

Spinal muscular atrophy (SMA) is a neurodegenerative disease characterized by the
selective loss of spinal motor neurons (MNs) and concomitant muscle weakness. Mutation of …