The role of Toll-like receptor 4 signaling pathway in ovarian, cervical, and endometrial cancers

LA Lupi, MS Cucielo, HS Silveira, LB Gaiotte… - Life sciences, 2020 - Elsevier
Toll-like receptors (TLRs) are critical sensors related to inflammation and tumorigenesis.
Among all subtypes, the TLR4 is a highly described transmembrane protein involved in the …

Human papillomavirus associated cervical lesion: pathogenesis and therapeutic interventions

J Ye, L Zheng, Y He, X Qi - MedComm, 2023 - Wiley Online Library
Human papillomavirus (HPV) is the most prevalent sexually transmitted virus globally.
Persistent high‐risk HPV infection can result in cervical precancerous lesions and cervical …

Availability, accessibility, and quality of adolescent Sexual and Reproductive Health (SRH) services in urban health facilities of Rwanda: a survey among social and …

P Ndayishimiye, R Uwase, I Kubwimana… - BMC Health Services …, 2020 - Springer
Background Adolescents are still getting pregnant and contracting Human
Immunodeficiency Virus (HIV) and Sexually Transmitted Infections (STIs) in Rwanda as …

Polymorphisms and haplotypes of TLR-4/9 associated with bacterial infection, gingival inflammation/recession and oral cancer

A Jha, N Nath, A Kumari, N Kumari, AK Panda… - … -Research and Practice, 2023 - Elsevier
Abstract Background The expression and SNPs of innate immunity genes TLR-4/9 for
bacterial infection, gingival inflammation/gingival recession (GIGR), and oral squamous cell …

Influence of TLR4 and TLR9 polymorphisms and haplotypes on multiple hrHPV infections and HPV16 copy number in cervical cancer and cervicitis

N Pandey, A Chauhan, N Raithatha, P Patel… - Microbial …, 2021 - Elsevier
Genetic polymorphism in pathogen recognition receptors tends to influence infection,
disease susceptibility, and progression. We analyzed the association of TLR4 and TLR9 …

Association of TLR4 and TLR9 gene polymorphisms with cervical HR-HPV infection status in Chinese Han population

C Zhang, Z Yang, P Luo, T Li, S Wang, F Sun… - BMC Infectious …, 2023 - Springer
Abstract Background Toll-like receptors (TLRs) may be involved in the natural history of
human papillomavirus (HPV) infection. In our study, we aimed to investigate the association …

Inflammatory responses during trichomoniasis: The role of Toll‐like receptors and inflammasomes

A Jafarzadeh, M Nemati, E Salarkia… - Parasite …, 2023 - Wiley Online Library
Toll‐like receptors (TLRs) and inflammasomes belong to the pattern recognition receptors
(PRRs) of innate immunity identifying conserved compounds produced by pathogens or …

[HTML][HTML] Innate immunity–the hallmark of Helicobacter pylori infection in pediatric chronic gastritis

LE Meliț, CO Mărginean, MO Săsăran… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Innate immunity was found to be associated with both persistence of
Helicobacter pylori (H. pylori) infection and increased risk of gastric cancer. AIM To identify …

TLR9 in the human papilloma virus infections: friend or foe?

B Douzandeh-Mobarrez, A Kariminik… - Viral …, 2022 - liebertpub.com
Immune system plays dual roles during human papilloma virus (HPV) infections, from
defense against the virus to induction or stimulation of the HPV-related cancers. It appears …

Polymorphisms and haplotypes of TLR4, TLR9 and CYP1A1 genes possibly interfere with high-risk human papillomavirus infection and cervical cancer susceptibility …

N Nath, P Mishra, AK Panda, R Mishra - International …, 2020 - Elsevier
Background Expression and single nucleotide polymorphisms (SNPs) of TLR4/9 and
CYP1A1 genes are vital for cervical squamous cell carcinoma (CSCC) but considerably vary …