[HTML][HTML] miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis

CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …

Identifying circulating microRNAs as biomarkers of cardiovascular disease: a systematic review

R Navickas, D Gal, A Laucevičius… - Cardiovascular …, 2016 - academic.oup.com
The aim of the present study is to identify microRNAs (miRs) with high potential to be used
as biomarkers in plasma and/or serum to clinically diagnose, or provide accurate prognosis …

Specific miRNA disease biomarkers in blood, serum and plasma: challenges and prospects

C Backes, E Meese, A Keller - Molecular diagnosis & therapy, 2016 - Springer
Significant effort has been devoted to discovering microRNA (miRNA) disease biomarkers.
In particular, miRNAs in whole blood or specific blood components are candidates for …

Methodological challenges in utilizing mi RNA s as circulating biomarkers

L Moldovan, KE Batte, J Trgovcich… - Journal of cellular …, 2014 - Wiley Online Library
Micro RNA s (mi RNA s) have emerged as important regulators in the post‐transcriptional
control of gene expression. The discovery of their presence not only in tissues but also in …

microRNAs in cardiovascular diseases: current knowledge and the road ahead

G Condorelli, MVG Latronico, E Cavarretta - Journal of the American …, 2014 - jacc.org
Over the last few years, the field of microribonucleic acid (miRNA) in cardiovascular biology
and disease has expanded at an incredible pace. miRNAs are themselves part of a larger …

Novel methodologies for biomarker discovery in atherosclerosis

IE Hoefer, S Steffens, M Ala-Korpela… - European heart …, 2015 - academic.oup.com
Identification of subjects at increased risk for cardiovascular events plays a central role in the
worldwide efforts to improve prevention, prediction, diagnosis, and prognosis of …

[HTML][HTML] MicroRNAs expression profiles in cardiovascular diseases

E Bronze-da-Rocha - BioMed research international, 2014 - hindawi.com
The current search for new markers of cardiovascular diseases (CVDs) is explained by the
high morbidity and mortality still observed in developed and developing countries due to …

Non-coding RNAs in cardiac remodeling and heart failure

R Kumarswamy, T Thum - Circulation research, 2013 - Am Heart Assoc
Heart failure is a leading cause of death in industrialized nations especially in an aging
population. The recent improvements in cardiac revascularization therapy reduced death …

[HTML][HTML] Epigenetic biomarkers in cardiovascular diseases

C Soler-Botija, C Gálvez-Montón… - Frontiers in genetics, 2019 - frontiersin.org
Cardiovascular diseases are the number one cause of death worldwide and greatly impact
quality of life and medical costs. Enormous effort has been made in research to obtain new …

Systematic review of microRNA biomarkers in acute coronary syndrome and stable coronary artery disease

A Kaur, ST Mackin, K Schlosser, FL Wong… - Cardiovascular …, 2020 - academic.oup.com
The aim of this systematic review was to assess dysregulated miRNA biomarkers in
coronary artery disease (CAD). Dysregulated microRNA (miRNAs) have been shown to be …