Omega-3 (ω-3) and omega-6 (ω-6) polyunsaturated fatty acids (PUFAs) are nowadays
desirable components of oils with special dietary and functional properties. Their therapeutic …

Adipose tissue metabolism is closely linked to insulin resistance, and differential fat
distributions are associated with disorders like hypertension, diabetes, and cardiovascular …

The permeability barrier is required for terrestrial life and is localized to the stratum corneum,
where extracellular lipid membranes inhibit water movement. The lipids that constitute the …

Sebaceous glands are intriguing glands that are found throughout the human body except
on the palms of the hands and soles of the feet. The true function of these glands has yet to …

Epoxyeicosatrienoic acids (EETs), which function primarily as autocrine and paracrine
mediators in the cardiovascular and renal systems, are synthesized from arachidonic acid by …

Long-chain fatty acids (FA) coordinately induce the expression of a panel of genes involved
in cellular FA metabolism in cardiac muscle cells, thereby promoting their own metabolism …

Linoleic acid (18: 2ω6) and α-linolenic acid (18: 3ω3) represent the parent fats of the two
main classes of polyunsaturated fatty acids: the ω-6 (n-6) and the ω-3 (n-3) fatty acids …

Keratinocyte differentiation is an essential process for epidermal stratification and stratum
corneum formation. Keratinocytes proliferate in the basal layer of the epidermis and start …

We show here that the α, β, and γ isotypes of peroxisome proliferator–activated receptor
(PPAR) are expressed in the mouse epidermis during fetal development and that they …

The peroxisome proliferator-activated receptors, PPARα, PPARβ, and PPARγ, are a family of
transcription factors activated by a diversity of molecules including fatty acids and fatty acid …