MicroRNAs (miRNAs) are conserved small non-coding RNAs that play an important role in
the regulation of gene expression and participate in a variety of biological processes. The …

Malfunction of nuclear–cytoplasmic transport contributes to many diseases including cancer.
Defective nuclear transport leads to changes in both the physiological levels and temporal …

Introduction AHSCT is the treatment of choice for newly diagnosed patients with transplant-
eligible multiple myeloma (MM). However, considerable variability in response to …

MicroRNAs (miRNAs) directly and indirectly affect tumorigenesis. To be able to perform their
myriad roles, miRNA machinery genes, such as Drosha, DGCR8, Dicer1, XPO5, TRBP, and …

Intensive research has been undertaken during the last decade to identify the implication of
microRNAs (miRNAs) in the pathogenesis of multiple myeloma (MM). The expression …

Introduction: Increasing evidence indicates that non-coding RNAs (ncRNAs) are aberrantly
expressed and/or functionally deregulated in hematological malignancies, including multiple …

KRT81 is involved in carcinogenesis and progression of many types of human cancers.
However, little is known about the role of KRT81 in melanoma. In this study, we identified …

Multiple myeloma (MM) is a common hematological malignancy that is often associated with
osteolytic lesions, anemia and renal impairment. Deregulation of miRNA has been …

Objective MicroRNA (miRNA)-related single-nucleotide polymorphisms (miR-SNPs) in
miRNA processing machinery genes can affect cancer risk, treatment efficacy, and patient …

Theragnostics represent cutting-edge, multi-disciplinary strategies that combine diagnostics
with therapeutics in order to generate personalized therapies that improve patient outcome …