The role of the Tear Film and Ocular Surface Society (TFOS) Dry Eye Workshop (DEWS) II
Diagnostic Methodology Subcommittee was 1) to identify tests used to diagnose and monitor …

There is a number of systemic diseases affecting the cornea. These include endocrine
disorders (diabetes, Graves' disease, Addison's disease, hyperparathyroidism), infections …

Cyclosporine has been used successfully as a systemic immunomodulator for more than two
decades, and numerous studies have investigated its mechanisms of action. In 2003 an …

Cyclosporine is an immunosuppressant agent approved for the treatment of dry eye disease
and used off-label for other ocular pathologies. Its formulation and ocular bioavailability …

Preferred Practice Pattern® guidelines are developed by the Academy's H. Dunbar Hoskins
Jr., MD Center for Quality Eye Care without any external financial support. Authors and …

Aims: To examine the efficacy of tacrolimus ophthalmic suspension 0.1% in treating severe
allergic conjunctivitis. Methods: This was a multicenter, randomized, double-masked …

Atopic keratoconjunctivitis is a chronic noninfectious inflammatory condition and is one of
the most severe ophthalmic complications associated with atopic dermatitis. It requires …

In this article, we provide the results of experimental studies demonstrating that corneal
avascularity is an active process involving the production of anti-angiogenic factors, which …

Vernal keratoconjunctivitis (VKC) is a bilateral, usually seasonally recurrent, allergic
inflammation of the conjunctiva, characterised by limbal gelatinous hypertrophy and/or …

Cyclosporine A (CsA) is an immunomodulatory agent that primarily inhibits the proliferation
and action of T cells. Systemic CsA has been used successfully in solid organ …