Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …

We rely on our visual system to cope with the vast barrage of incoming light patterns and to
extract features from the scene that are relevant to our well-being. The necessary reduction …

Neuro-inspired vision systems hold great promise to address the growing demands of mass
data processing for edge computing, a distributed framework that brings computation and …

Life on earth is subject to alternating cycles of day and night imposed by the rotation of the
earth. Consequently, living things have evolved photodetective systems to synchronize their …

The rhodopsin crystal structure provides a structural basis for understanding the function of
this and other G protein–coupled receptors (GPCRs). The major structural motifs observed …

CNS axons differ in diameter (d) by nearly 100-fold (∼ 0.1–10 μm); therefore, they differ in
cross-sectional area (d 2) and volume by nearly 10,000-fold. If, as found for optic nerve …

Synaptic interactions to extract information about wavelength, and thus color, begin in the
vertebrate retina with three classes of light-sensitive cells: rod photoreceptors at low light …

The fovea is a specialized region of the retina that dominates the visual perception of
primates by providing high chromatic and spatial acuity. While the foveal and peripheral …

Abstract CaBP1–8 are neuronal Ca2+-binding proteins with similarity to calmodulin (CaM).
Here we show that CaBP4 is specifically expressed in photoreceptors, where it is localized …

Amacrine cells represent the most diverse class of retinal neuron, comprising dozens of
distinct cell types. Each type exhibits a unique morphology and generates specific visual …