Extracellular vesicles in the pathogenesis and treatment of acute lung injury
Q Hu, S Zhang, Y Yang, JQ Yao, WF Tang… - Military Medical …, 2022 - Springer
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common life-
threatening lung diseases associated with acute and severe inflammation. Both have high …
threatening lung diseases associated with acute and severe inflammation. Both have high …
Mitochondrial dynamics and mitophagy in lung disorders
Mitochondria are biosynthetic, bioenergetic, and signaling organelles which are critical for
physiological adaptations and cellular stress responses to the environment. Various …
physiological adaptations and cellular stress responses to the environment. Various …
Bone marrow mesenchymal stem cell-derived extracellular vesicle infusion for the treatment of respiratory failure from COVID-19: a randomized, placebo-controlled …
AL Lightner, V Sengupta, S Qian, JT Ransom, S Suzuki… - Chest, 2023 - Elsevier
Background Bone marrow mesenchymal stem cell (BM-MSC)-derived extracellular vesicles
(ExoFlo) convey the immunomodulatory and regenerative properties of intact BM-MSCs …
(ExoFlo) convey the immunomodulatory and regenerative properties of intact BM-MSCs …
Stem cell-derived extracellular vesicles as new tools in regenerative medicine-immunomodulatory role and future perspectives
E Karnas, P Dudek, EK Zuba-Surma - Frontiers in immunology, 2023 - frontiersin.org
In the last few decades, the practical use of stem cells (SCs) in the clinic has attracted
significant attention in the regenerative medicine due to the ability of these cells to proliferate …
significant attention in the regenerative medicine due to the ability of these cells to proliferate …
Ulinastatin protects against LPS-induced acute lung injury by attenuating TLR4/NF-κB pathway activation and reducing inflammatory mediators
C Cao, C Yin, S Shou, J Wang, L Yu, X Li, Y Chai - Shock, 2018 - journals.lww.com
Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome, remain the
leading causes of morbidity and mortality in intensive care units. Ulinastatin (UTI), a serine …
leading causes of morbidity and mortality in intensive care units. Ulinastatin (UTI), a serine …
Mouse models of acute respiratory distress syndrome: a review of analytical approaches, pathologic features, and common measurements
F Aeffner, B Bolon, IC Davis - Toxicologic pathology, 2015 - journals.sagepub.com
Acute respiratory distress syndrome (ARDS) is a severe pulmonary reaction requiring
hospitalization, which is incited by many causes, including bacterial and viral pneumonia as …
hospitalization, which is incited by many causes, including bacterial and viral pneumonia as …
Heme oxygenase-1 (HO-1) regulates Golgi stress and attenuates endotoxin-induced acute lung injury through hypoxia inducible factor-1α (HIF-1α)/HO-1 signaling …
X Li, J Yu, L Gong, Y Zhang, S Dong, J Shi, C Li… - Free Radical Biology …, 2021 - Elsevier
Sepsis caused acute lung injury (ALI) is a kind of serious disease in critically ill patients with
very high morbidity and mortality. Recently, it has been demonstrated that Golgi is involved …
very high morbidity and mortality. Recently, it has been demonstrated that Golgi is involved …
[HTML][HTML] Aspiration syndromes and associated lung injury: incidence, pathophysiology and management
P Kosutova, P Mikolka - Physiological Research, 2021 - ncbi.nlm.nih.gov
Aspiration is a common condition affecting healthy or sick patients which could create an
acute or chronic inflammatory reaction in the lungs. Aspiration syndromes could be …
acute or chronic inflammatory reaction in the lungs. Aspiration syndromes could be …
Extracellular vesicle-encapsulated CC16 as novel nanotherapeutics for treatment of acute lung injury
Acute lung injury (ALI) is still associated with high mortality. Growing evidence suggests that
Club Cell Protein 16 (CC16) plays a protective role against ALI. However, the doses of …
Club Cell Protein 16 (CC16) plays a protective role against ALI. However, the doses of …
Emodin ameliorates LPS-induced acute lung injury, involving the inactivation of NF-κB in mice
Acute lung injury (ALI) and its severe manifestation of acute respiratory distress syndrome
(ARDS) are well-known illnesses. Uncontrolled and self-amplified pulmonary inflammation …
(ARDS) are well-known illnesses. Uncontrolled and self-amplified pulmonary inflammation …