Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and
an angiogenic inducer in a variety of in vivo models. Hypoxia has been shown to be a major …

Endothelial cell migration is essential to angiogenesis. This motile process is directionally
regulated by chemotactic, haptotactic, and mechanotactic stimuli and further involves …

Endothelial nitric oxide synthase (eNOS) is the nitric oxide synthase isoform responsible for
maintaining systemic blood pressure, vascular remodelling and angiogenesis,,,. eNOS is …

Angiogenic growth factors such as fibroblast growth factors (FGFs) and vascular endothelial
growth factors (VEGFs) are currently targets of intense efforts to inhibit deregulated blood …

Infantile haemangiomas (IH) are the most common benign tumours of infancy. Although
most IH are innocuous and 85–90% regress spontaneously, some may become life‐or …

Vascular endothelial growth factor (VEGF) was originally identified as an endothelial cell
specific growth factor stimulating angiogenesis and vascular permeability. Some family …

Background—Although myocardial ischemia is known to be significantly related to the
development of coronary collateral vessels (CCVs), there is considerable variation between …

Exercise and muscle contractions create a powerful stimulus for structural remodeling of the
vasculature. An increase in flow velocity through a vessel increases shear stress, a major …

Stenting is the primary treatment for vascular obstruction-related cardiovascular diseases,
but it inevitably causes endothelial injury which may lead to severe thrombosis and …

It has long been known that endothelial Ca2+ signals drive angiogenesis by recruiting
multiple Ca2+-sensitive decoders in response to pro-angiogenic cues, such as vascular …