The glycome describes the complete repertoire of glycoconjugates composed of
carbohydrate chains, or glycans, that are covalently linked to lipid or protein molecules …

Ageing and age-related diseases share some basic mechanistic pillars that largely
converge on inflammation. During ageing, chronic, sterile, low-grade inflammation—called …

Abstract The Immunoglobulin G (IgG) glycome is well known for its heterogeneity and shows
a significant degree of variation within populations. IgG glycome composition is influenced …

Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …

The presence of fucose on IgG1 Asn-297 N-linked glycan is the modification of the human
IgG1 Fc structure with the most significant impact on FcɣRIII affinity. It also significantly …

N‐glycosylation is a ubiquitous protein modification, and N‐glycosylation profiles are
emerging as both biomarkers and functional effectors in various types of diabetes. Genome …

Immunoglobulin A (IgA) mediates mucosal responses to food antigens and the intestinal
microbiome and is involved in susceptibility to mucosal pathogens, celiac disease …

Post-translational modifications diversify protein functions and dynamically coordinate their
signalling networks, influencing most aspects of cell physiology. Nevertheless, their genetic …

Effector functions of immunoglobulin G (IgG) are regulated by the composition of a glycan
moiety, thus affecting activity of the immune system. Aberrant glycosylation of IgG has been …

N-glycosylation is a frequent modification of proteins, essential for all domains of life. N-
glycan biosynthesis is a dynamic, complex, non-templated process, wherein specific …