Background Benzodiazepine misuse is a growing public health problem, with increases in
benzodiazepine-related overdose deaths and emergency room visits in recent years …

This paper reviews studies examining the pharmacological interactions and epidemiology of
the combined use of opioids and benzodiazepines (BZDs). A search of English language …

Background Benzodiazepines (BZDs) have a sedative and hypnotic effect upon people.
Short term use can be beneficial but long term BZD use is common, with several risks in …

The purposes of this study were to examine predictors of benzodiazepine use among
methadone maintenance treatment patients, to determine whether baseline benzodiazepine …

Objective There is a significant interindividual variability in treatment outcomes in
methadone maintenance treatment (MMT) for opioid use disorder (OUD). This prospective …

Background Over the past decade, patients admitted to addiction treatment programs have
reported increasing rates of concurrent opioid and benzodiazepine (BZD) use. This drug …

Context Ramelteon is a novel MT 1 and MT 2 melatonin receptor selective agonist recently
approved for insomnia treatment. Most approved insomnia medications have potential for …

BACKGROUND: Previous studies from North America, Europe and Australia have reported
high levels of benzodiazepine use among opiate-dependent patients in opiate maintenance …

Background: Rates of cannabis use among patients receiving methadone maintenance
therapy are high, and cannabis use may be associated with outcomes of methadone …

Benzodiazepine (BZD) use is widespread among opioid-maintained patients worldwide. We
conducted a cross-sectional survey to investigate motives and patterns of BZD use and …