A clinical approach to diagnosis of autoimmune encephalitis

F Graus, MJ Titulaer, R Balu, S Benseler… - The lancet …, 2016 - thelancet.com
Encephalitis is a severe inflammatory disorder of the brain with many possible causes and a
complex differential diagnosis. Advances in autoimmune encephalitis research in the past …

Autoantibodies to synaptic receptors and neuronal cell surface proteins in autoimmune diseases of the central nervous system

J Dalmau, C Geis, F Graus - Physiological reviews, 2017 - journals.physiology.org
Investigations in the last 10 years have revealed a new category of neurological diseases
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …

[HTML][HTML] Long COVID hallmarks on [18F] FDG-PET/CT: a case-control study

M Sollini, S Morbelli, M Ciccarelli, M Cecconi… - European Journal of …, 2021 - Springer
Purpose The present study hypothesised that whole-body [18F] FDG-PET/CT might provide
insight into the pathophysiology of long COVID. Methods We prospectively enrolled 13 adult …

Infections, inflammation and epilepsy

A Vezzani, RS Fujinami, HS White, PM Preux… - Acta …, 2016 - Springer
Epilepsy is the tendency to have unprovoked epileptic seizures. Anything causing structural
or functional derangement of brain physiology may lead to seizures, and different conditions …

The clinical spectrum of Caspr2 antibody–associated disease

A van Sonderen, H Ariño, M Petit-Pedrol, F Leypoldt… - Neurology, 2016 - AAN Enterprises
Objective: To report a large cohort of patients with antibodies against contactin-associated
protein-like 2 (Caspr2) and provide the clinical spectrum of this disorder. Methods: Serum …

Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAA receptor: a case series, characterisation of the antigen, and analysis of the …

M Petit-Pedrol, T Armangue, X Peng, L Bataller… - The lancet …, 2014 - thelancet.com
Background Increasing evidence suggests that seizures and status epilepticus can be
immune-mediated. We aimed to describe the clinical features of a new epileptic disorder …

Autoimmune encephalopathies

F Leypoldt, T Armangue… - Annals of the New York …, 2015 - Wiley Online Library
Over the past 10 years, the continual discovery of novel forms of encephalitis associated
with antibodies to cell‐surface or synaptic proteins has changed the paradigms for …

Autoimmune encephalitis: pathophysiology and imaging review of an overlooked diagnosis

BP Kelley, SC Patel, HL Marin… - American Journal …, 2017 - Am Soc Neuroradiology
Autoimmune encephalitis is a relatively new category of immune-mediated disease
involving the central nervous system that demonstrates a widely variable spectrum of clinical …

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's …

SR Irani, S Alexander, P Waters, KA Kleopa, P Pettingill… - Brain, 2010 - academic.oup.com
Antibodies that immunoprecipitate 125I-α-dendrotoxin-labelled voltage-gated potassium
channels extracted from mammalian brain tissue have been identified in patients with …

Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series

M Lai, MGM Huijbers, E Lancaster, F Graus… - The Lancet …, 2010 - thelancet.com
Background Voltage-gated potassium channels are thought to be the target of antibodies
associated with limbic encephalitis. However, antibody testing using cells expressing …