Synthesis of Oxacycles Employing the Oxa‐Pictet–Spengler Reaction: Recent Developments and New Prospects

EL Larghi, TS Kaufman - European Journal of Organic …, 2011 - Wiley Online Library
Abstract The oxa‐Pictet–Spengler cyclization is the oxygen variation of the Pictet–Spengler
reaction, in which an aromatic alcohol component (generally a β‐arylethyl alcohol) reacts …

Synthesis and contractile activity of substituted 1, 2, 3, 4-tetrahydroisoquinolines

I Ivanov, S Nikolova, D Aladjov, I Stefanova… - Molecules, 2011 - mdpi.com
A series of different 1-monosubstituted and 1, 1-disubstituted 1, 2, 3, 4-tetrahydro-
isoquinolines was synthesized in high yields from different ketoamides. We have developed …

Two new phenylpropanoids and a new dihydrostilbenoid from the flower buds of Magnolia biondii pamp and their acetylcholinesterase inhibitory activities

YG Cao, HW Li, B Cao, JC Wang, YL Zhang… - Natural Product …, 2021 - Taylor & Francis
Abstract Two new phenylpropanoids, named (2'R*, 3'R*)-2', 3'-dihydroxy-4'-methoxy-caffeoyl
butyrate (1), 9-acetoxy syringin (2), and a new dihydrostilbene, named (8'R)-4', 5-dihydroxy …

Synthesis of isochromans via Fe (OTf) 2-catalyzed Oxa-Pictet–Spengler cyclization

J Zhou, C Wang, D Xue, W Tang, J Xiao, C Li - Tetrahedron, 2018 - Elsevier
Fe (OTf) 2 has been found to be an efficient catalyst for the Oxa-Pictet–Spengler cyclization
reaction leading to isochromans. A series of substituted isochromans were obtained with …

Synthesis of 2, 3-Benzodiazepines and 2, 3-Benzodiazepin-4-ones from Arynes and β-Diketones

K Okuma, Y Tanabe, N Nagahora… - Bulletin of the Chemical …, 2015 - academic.oup.com
Benzodiazepines were synthesized by two-step or one-pot reactions from aryne precursors.
Reaction of 2-(trimethylsilyl) aryl triflates with β-diketones in the presence of CsF gave ortho …

[PDF][PDF] Synthesis of isochromanes and isothiochromanes bearing fluorinated one-carbon units via intramolecular cyclizations of ortho-substituted α-(trifluoromethyl) …

市川淳士, イチカワジュンジ - Heterocycles, 2009 - tsukuba.repo.nii.ac.jp
α-(Trifluoromethyl) styrenes bearing a nucleophilic oxygen or sulfur atom tethered by a
methylene or methyne unit at the ortho carbon were prepared by the coupling reaction of 2 …

Selective Reduction of ortho-Acylated β-Enaminones of Homoveratryamine and Their Cyclization to 1,2,3,4-Tetrahydroisoquinolines with β-Enaminone Moiety

S Nikolova, E Kochovska, I Ivanov - Synthetic Communications, 2013 - Taylor & Francis
Enaminones are very stable compounds and can be prepared from cheap and easily
available starting materials. Therefore they are excellent starting materials in organic …

Synthesis of N-[1-(2-Acetyl-4,5-dimethoxyphenyl)propan-2-yl]benzamide and Its Copper(II) Complex

P Marinova, S Nikolova, S Tsoneva - Russian Journal of General …, 2023 - Springer
This paper represents a convenient method for the synthesis of N-[1-(2-acetyl-4, 5-
dimethoxyphenyl) propan-2-yl] benzamide and its Cu (II) complex. In silico analysis …

[PDF][PDF] Microwave assisted synthesis of 1-substituted 6, 7-dimethoxy-3-oxo-2, 3-dihydroisoquinolines under solvent free conditions as potential antimicrobial agents …

AU Borse, NL Patil, MN Patil, SR Tetgure, AP Nikum… - J Pharm Res, 2012 - researchgate.net
ABSTRACT A convenient synthesis of 1-substituted 6, 7-dimethoxy-3-oxo-2, 3-
dihydroisoquinolines (4a-i) is developed under microwave irradiation, starting from ethyl 2 …

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T Ishikawa, M Tomatsu, H Nagase, H Fujii - triggered.edina.clockss.org
HeteroCycles logo2 logo2 HETEROCYCLES An International Journal for Reviews and
Communications in Heterocyclic Chemistry Web Edition ISSN: 1881-0942 Published online by …