COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives
Abstract Coronavirus disease 2019 (COVID-19), caused by a strain of coronavirus known as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global …
Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)
AR Bourgonje, AE Abdulle, W Timens… - The Journal of …, 2020 - Wiley Online Library
Abstract Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional
host receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus …
host receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus …
Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system: celebrating the 20th anniversary of the discovery of ACE2
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that
revolve around its trivalent function: a negative regulator of the renin-angiotensin system …
revolve around its trivalent function: a negative regulator of the renin-angiotensin system …
The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2
An acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that surfaced in China in late 2019, continues to spread rapidly across the …
(SARS-CoV-2) that surfaced in China in late 2019, continues to spread rapidly across the …
Use of renin–angiotensin–aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study
FJ de Abajo, S Rodríguez-Martín, V Lerma… - The Lancet, 2020 - thelancet.com
Background Concerns have been raised about the possibility that inhibitors of the renin–
angiotensin–aldosterone system (RAAS) could predispose individuals to severe COVID-19; …
angiotensin–aldosterone system (RAAS) could predispose individuals to severe COVID-19; …
Renin–angiotensin–aldosterone system inhibitors in patients with Covid-19
RAAS Inhibitors in Patients with Covid-19 The effects of renin–angiotensin–aldosterone
system blockers on angiotensin-converting enzyme 2 levels and activity in humans are …
system blockers on angiotensin-converting enzyme 2 levels and activity in humans are …
Hypertension, the renin–angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19: European Society of …
Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of
mortality worldwide, and its importance is further emphasized in the context of the novel …
mortality worldwide, and its importance is further emphasized in the context of the novel …
Continuation versus discontinuation of renin–angiotensin system inhibitors in patients admitted to hospital with COVID-19: a prospective, randomised, open-label trial
Background Biological considerations suggest that renin–angiotensin system inhibitors
might influence the severity of COVID-19. We aimed to evaluate whether continuing versus …
might influence the severity of COVID-19. We aimed to evaluate whether continuing versus …
Counter-regulatory renin–angiotensin system in cardiovascular disease
M Paz Ocaranza, JA Riquelme, L García… - Nature Reviews …, 2020 - nature.com
The renin–angiotensin system is an important component of the cardiovascular system.
Mounting evidence suggests that the metabolic products of angiotensin I and II—initially …
Mounting evidence suggests that the metabolic products of angiotensin I and II—initially …
Hypertension and related diseases in the era of COVID-19: a report from the Japanese Society of Hypertension Task Force on COVID-19
S Shibata, H Arima, K Asayama, S Hoshide… - Hypertension …, 2020 - nature.com
Abstract Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has affected more than seven million people …
syndrome coronavirus 2 (SARS-CoV-2), has affected more than seven million people …