Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …

The aim of the current study was twofold:(1) to systematically examine differences in fear
conditioning between anxiety patients and healthy controls using meta‐analytic methods …

The adaptive regulation of fear memories is a crucial neural function that prevents
inappropriate fear expression. Fear memories can be acquired through contextual fear …

Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …

Fear can be an adaptive emotion that helps defend against potential danger. Classical
conditioning models elegantly describe how animals learn which stimuli in the environment …

Fear generalization, in which conditioned fear responses generalize or spread to related
stimuli, is a defining feature of anxiety disorders. The behavioral consequences of …

Learning to predict threat is essential, but equally important—yet often overlooked—is
learning about the absence of threat. Here, by recording neural activity in two nucleus …

Objective: Heightened generalization of fear from an aversively reinforced conditioned
stimulus (CS+, a conditioned danger cue) to resembling stimuli is widely accepted as a …

Generalization of conditioned fear is adaptive in some situations but maladaptive when fear
excessively generalizes to innocuous stimuli with incidental resemblance to a genuine …

Pathological anxiety and chronic stress lead to structural degeneration and impaired
functioning of the hippocampus and the PFC, which may account for the increased risk of …