Drug resistance in protozoan parasites: an incessant wrestle for survival

PK Pramanik, MN Alam, DR Chowdhury… - Journal of Global …, 2019 - Elsevier
Nowadays, drug resistance in parasites is considered to be one of the foremost concerns in
health and disease management. It is interconnected worldwide and undermines the health …

Molecular biology of the amitochondriate parasites, Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis

S Vanacova, DR Liston, J Tachezy… - International journal for …, 2003 - Elsevier
The amitochondriates are an assembly of unicellular protists that lack mitochondria, and
often other typical eukaryotic organelles, such as peroxisomes. Relatively little research has …

Entamoeba histolytica : a novel cysteine protease and an adhesin form the 112 kDa surface protein

G Garcia‐Rivera, MA Rodriguez, R Ocadiz… - Molecular …, 1999 - Wiley Online Library
Here, we present evidence that a cysteine protease (EhCP112) and a protein with an
adherence domain (EhADH112) form the Entamoeba histolytica 112 kDa adhesin …

Transcriptional Silencing of an Amoebapore Gene in Entamoeba histolytica: Molecular Analysis and Effect on Pathogenicity

R Bracha, Y Nuchamowitz, D Mirelman - Eukaryotic Cell, 2003 - Am Soc Microbiol
Transcriptional silencing of the gene coding for amoebapore A (AP-A) was observed when
trophozoites of Entamoeba histolytica were transfected with a hybrid plasmid construct …

Regulation of gene expression in protozoa parasites

C Gomez, M Esther Ramirez… - BioMed Research …, 2010 - Wiley Online Library
Infections with protozoa parasites are associated with high burdens of morbidity and
mortality across the developing world. Despite extensive efforts to control the transmission of …

Multidrug resistance in the protozoan parasite Entamoeba histolytica

E Orozco, C Lopez, C Gomez, DG Perez… - Parasitology …, 2002 - Elsevier
In this review we discuss the mechanisms and molecules involved in the multidrug
resistance (MDR) of the protozoan parasite Entamoeba histolytica. Drug resistant mutants …

Virulence factors of Entamoeba histolytica

CA Gilchrist, WA Petri Jr - Current opinion in microbiology, 1999 - Elsevier
Recent studies have increased our knowledge of Entamoeba histolytica cell biology and
gene regulation. In the ameba, dominant-negative mutations in the Gal/GalNAc lectin affect …

Multidrug resistance in amoebiasis patients

D Bansal, R Sehgal, Y Chawla, N Malla… - Indian Journal of …, 2006 - journals.lww.com
Methods: Forty five clinical isolates of Entamoeba sp.[E. histolytica (15) and E. dispar (30)]
were maintained in polyxenic followed by monoxenic medium. DNA and total RNA were …

Ehp53, an Entamoeba histolytica protein, ancestor of the mammalian tumour suppressor p53

L Mendoza, E Orozco, MA Rodriguez… - …, 2003 - microbiologyresearch.org
This paper reports the identification of Ehp53, a p53-like Entamoeba histolytica protein,
which binds to the human p53 DNA consensus sequence (oli-p53). Monoclonal antibodies …

Serum-Dependent Selective Expression of EhTMKB1-9, a Member of Entamoeba histolytica B1 Family of Transmembrane Kinases

S Shrimal, S Bhattacharya, A Bhattacharya - PLoS pathogens, 2010 - journals.plos.org
Entamoeba histolytica transmembrane kinases (EhTMKs) can be grouped into six distinct
families on the basis of motifs and sequences. Analysis of the E. histolytica genome …