Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

Basic biology and role of interleukin‐17 in immunity and inflammation

C Zenobia, G Hajishengallis - Periodontology 2000, 2015 - Wiley Online Library
Interleukin‐17 (also known as interleukin‐17A) is a key cytokine that links T‐cell activation to
neutrophil mobilization and activation. As such, interleukin‐17 can mediate protective innate …

Maintaining homeostatic control of periodontal bone tissue

JD Hathaway‐Schrader, CM Novince - Periodontology 2000, 2021 - Wiley Online Library
Alveolar bone is a unique osseous tissue due to the proximity of dental plaque biofilms.
Periodontal health and homeostasis are mediated by a balanced host immune response to …

Inflammatory mediators in the pathogenesis of periodontitis

T Yucel-Lindberg, T Båge - Expert reviews in molecular medicine, 2013 - cambridge.org
Periodontitis is a chronic inflammatory condition of the periodontium involving interactions
between bacterial products, numerous cell populations and inflammatory mediators. It is …

Is inflammation a friend or foe for orthodontic treatment?: Inflammation in orthodontically induced inflammatory root resorption and accelerating tooth movement

M Yamaguchi, S Fukasawa - International journal of molecular sciences, 2021 - mdpi.com
The aim of this paper is to provide a review on the role of inflammation in orthodontically
induced inflammatory root resorption (OIIRR) and accelerating orthodontic tooth movement …

IL‐17: overview and role in oral immunity and microbiome

L Abusleme, NM Moutsopoulos - Oral diseases, 2017 - Wiley Online Library
Interleukin‐17 (IL‐17) is a multifaceted cytokine with diverse roles in both immune protection
and also immunopathology. IL‐17 has a well‐recognized role in immune surveillance at …

Oral dysbiosis and autoimmunity: from local periodontal responses to an imbalanced systemic immunity. A review

LJ Suárez, H Garzón, S Arboleda… - Frontiers in …, 2020 - frontiersin.org
The current paradigm of onset and progression of periodontitis includes oral dysbiosis
directed by inflammophilic bacteria, leading to altered resolution of inflammation and lack of …

The presence, function and regulation of IL‐17 and Th17 cells in periodontitis

WC Cheng, FJ Hughes… - Journal of clinical …, 2014 - Wiley Online Library
Periodontitis (PD) is a chronic inflammatory disease characterised by tissue inflammation
and destruction of the associated alveolar bone. It is caused by the colonisation of the …

Serum levels of cytokines in subjects with generalized chronic and aggressive periodontitis before and after non‐surgical periodontal therapy: a pilot study

PM Duarte, M da Rocha, E Sampaio… - Journal of …, 2010 - Wiley Online Library
Background: The emergence of periodontal medicine has increased interest in defining the
serologic profiles of inflammatory mediators in subjects with periodontitis. Thus, the aim of …

Clinical associations between IL-17 family cytokines and periodontitis and potential differential roles for IL-17A and IL-17E in periodontal immunity

R Azman, DF Lappin, A MacPherson, M Riggio… - Inflammation …, 2014 - Springer
Objective IL-17A is implicated in periodontitis pathogenesis. The roles of IL-17B–IL-17F and
IL-17A/F are unknown. This study aimed to determine clinical associations between IL-17 …