Despite decades of research on necrotizing enterocolitis, we still do not fully understand the
pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of …

NEC is a devastating disease that, once present, is very difficult to treat. In the absence of an
etiologic treatment, preventive measures are required. Advances in decoding the …

Preterm birth is the leading cause of infant morbidity and mortality. Necrotizing enterocolitis
(NEC) is an inflammatory bowel disease affecting primarily premature infants, which can be …

Abstract Background Pigs (Sus scrofa) provide relevant biomedical models to dissect
complex diseases due to their anatomical, genetic, and physiological similarities with …

Background Efforts to improve animal health, and understand genetic bases for production,
may benefit from a comprehensive analysis of animal genomes and epigenomes. Although …

Embryonic exposure to environmental chemicals may result in specific chronic diseases in
adulthood. Parabens, a type of environmental endocrine disruptors widely used in …

Background Although sperm DNA methylation has been studied in humans and other
species, its status in cattle is largely unknown. Results Using whole-genome bisulfite …

The incidence of pediatric inflammatory bowel disease (IBD), which includes Crohn disease
and ulcerative colitis, has risen alarmingly in the Western and developing world in recent …

Background: Epigenetic changes, such as DNA methylation, may contribute to an increased
susceptibility for developing necrotizing enterocolitis (NEC) in preterm infants. We assessed …

Abstract Background Differences in 5-hydroxymethylcytosine, 5hmC, distributions may
complicate previous observations of abnormal cytosine methylation statuses that are used …