The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Exercise is an effective strategy for preventing and treating obesity and its related
cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue …

Within adipose tissue (AT), immune cells and parenchymal cells closely interact creating a
complex microenvironment. In obesity, immune cell derived inflammation contributes to …

The peritoneal cavity is a fluid filled space that holds most of the abdominal organs,
including the omentum, a visceral adipose tissue that contains milky spots or clusters of …

Cardiac fibrosis is a significant global health problem associated with nearly all forms of
heart disease. In the heart interstitial fibrosis may be reparative, replacing areas damaged …

IL-33 plays a significant role in inflammation, allergy, and host defence against parasitic
helminths. The model gastrointestinal nematode Heligmosomoides polygyrus bakeri …

Obesity has a strong impact on the pathogenesis of cardiovascular disease, which raises
enthusiasm to understand how excess adiposity causes vascular injury. Adipose tissue is an …

Abstract Objective Interleukin-33 (IL-33) is associated with obesity-related inflammation. We
aim to investigate IL-33 expression in subcutaneous adipose tissue (SAT) in type 2 diabetes …

When discovered in the early 2000s, interleukin-33 (IL-33) was characterized as a potent
driver of type 2 immunity and implicated in parasite clearance, as well as asthma, allergy …

Perivascular adipose tissue (PVAT) depots are metabolically active and play a major
vasodilator role in healthy lean individuals. In obesity, they become inflamed and eosinophil …