Drug combinations for inhalation: Current products and future development addressing disease control and patient compliance

H Banat, R Ambrus, I Csóka - International Journal of Pharmaceutics, 2023 - Elsevier
Pulmonary delivery is an alternative route of administration with numerous advantages over
conventional routes of administration. It provides low enzymatic exposure, fewer systemic …

The role of beta-adrenergic receptors in depression and resilience

H Zhang, M Cui, JL Cao, MH Han - Biomedicines, 2022 - mdpi.com
Norepinephrine is a catecholamine neurotransmitter that has been extensively implicated in
the neurobiology of major depressive disorder (MDD). An accumulating body of evidence …

Inhalation of nebulized omega-3 fatty acids mitigate LPS-induced acute lung inflammation in rats: Implications for treatment of COPD and COVID-19

C Kocherlakota, B Nagaraju, N Arjun, A Srinath… - … and essential fatty acids, 2022 - Elsevier
Many current treatment options for lung inflammation and thrombosis come with unwanted
side effects. The natural omega-3 fatty acids (O3FA) are generally anti-inflammatory and …

Drug-drug interactions among patients hospitalized with COVID-19 in Greece

M Spanakis, P Ioannou, S Tzalis, V Papakosta… - Journal of Clinical …, 2022 - mdpi.com
The modulation of the pharmacological action of drugs due to drug-drug interactions (DDIs)
is a critical issue in healthcare. The aim of this study was to evaluate the prevalence and the …

Pharmacotherapies in older adults with COPD: challenges and opportunities

MG Matera, NA Hanania, M Maniscalco, M Cazzola - Drugs & aging, 2023 - Springer
Older adults have a higher prevalence of chronic obstructive pulmonary disease (COPD),
which will likely increase substantially in the coming decades owing to aging populations …

[HTML][HTML] Drug-drug interactions in polypharmacy patients: The impact of renal impairment

B Papotti, C Marchi, MP Adorni, F Potì - Current research in pharmacology …, 2021 - Elsevier
Chronic kidney disease (CKD) is a long-term condition characterized by a gradual loss of
kidney functions, usually accompanied by other comorbidities including cardiovascular …

Potentially inappropriate medications involved in drug–drug interactions at hospital discharge in Croatia

I Marinović, V Bačić Vrca, I Samardžić… - International journal of …, 2021 - Springer
Background The potentially inappropriate medications (PIMs) and drug–drug interactions
(DDIs) can significantly affect patient safety in the elderly, especially at transition of health …

Unraveling the Impact of Salbutamol Polytherapy: Clinically Relevant Drug Interactions

L Marques, N Vale - Future Pharmacology, 2023 - mdpi.com
The proper drug choice determines the treatment quality for a disease. The
pharmacotherapeutic strategy for respiratory diseases often involves the combination of …

Urine metabolomics signature reveals novel determinants of adrenal suppression in children taking inhaled corticosteroids to control asthma symptoms

DT Tran, Y Chen, Y Zheng, J Hecker… - Immunity …, 2024 - Wiley Online Library
Background Asthma is routinely treated with inhaled corticosteroids (ICS). Asthma patients
on ICS are at increased risk of adrenal suppression, a potentially serious effect of long‐term …

Impact of chronic medications in the perioperative period: mechanisms of action and adverse drug effects (Part I)

OL Elvir-Lazo, PF White, H Cruz Eng… - Postgraduate …, 2021 - Taylor & Francis
Background: This review article discusses the pharmacology of the most commonly used
chronic medications in patients undergoing elective surgical procedures. The mechanism of …