Towards an evolutionary theory of stress responses
All organisms have a stress response system to cope with environmental threats, yet its
precise form varies hugely within and across individuals, populations, and species. While …
precise form varies hugely within and across individuals, populations, and species. While …
[HTML][HTML] Survival assays using Caenorhabditis elegans
Caenorhabditis elegans is an important model organism with many useful features,
including rapid development and aging, easy cultivation, and genetic tractability. Survival …
including rapid development and aging, easy cultivation, and genetic tractability. Survival …
Xenobiotic metabolism and transport in Caenorhabditis elegans
JH Hartman, SJ Widmayer… - Journal of Toxicology …, 2021 - Taylor & Francis
Caenorhabditis elegans has emerged as a major model in biomedical and environmental
toxicology. Numerous papers on toxicology and pharmacology in C. elegans have been …
toxicology. Numerous papers on toxicology and pharmacology in C. elegans have been …
Healthspan Maintenance and Prevention of Parkinson's-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in C. elegans
G Brunetti, G Di Rosa, M Scuto, M Leri… - International journal of …, 2020 - mdpi.com
Numerous studies highlighted the beneficial effects of the Mediterranean diet (MD) in
maintaining health, especially during ageing. Even neurodegeneration, which is part of the …
maintaining health, especially during ageing. Even neurodegeneration, which is part of the …
Environmental stresses induce transgenerationally inheritable survival advantages via germline-to-soma communication in Caenorhabditis elegans
S Kishimoto, M Uno, E Okabe, M Nono… - Nature …, 2017 - nature.com
Hormesis is a biological phenomenon, whereby exposure to low levels of toxic agents or
conditions increases organismal viability. It thus represents a beneficial aspect of adaptive …
conditions increases organismal viability. It thus represents a beneficial aspect of adaptive …
[HTML][HTML] Mitochondrial stress restores the heat shock response and prevents proteostasis collapse during aging
J Labbadia, RM Brielmann, MF Neto, YF Lin… - Cell reports, 2017 - cell.com
In Caenorhabditis elegans, the programmed repression of the heat shock response (HSR)
accompanies the transition to reproductive maturity, leaving cells vulnerable to …
accompanies the transition to reproductive maturity, leaving cells vulnerable to …
[HTML][HTML] Recent progress in regulation of aging by insulin/IGF-1 signaling in Caenorhabditis elegans
H Lee, SJV Lee - Molecules and cells, 2022 - Elsevier
Caenorhabditis elegans has been used as a major model organism to identify genetic
factors that regulate organismal aging and longevity. Insulin/insulin-like growth factor 1 (IGF …
factors that regulate organismal aging and longevity. Insulin/insulin-like growth factor 1 (IGF …
Working with Worms: Caenorhabditis elegans as a Model Organism
PM Meneely, CL Dahlberg… - Current Protocols …, 2019 - Wiley Online Library
Since its introduction as a laboratory organism 50 years ago, the nematode worm
Caenorhabditis elegans has become one of the most widely used and versatile models for …
Caenorhabditis elegans has become one of the most widely used and versatile models for …
C. elegans as a model in developmental neurotoxicology
JA Ruszkiewicz, A Pinkas, MR Miah, RL Weitz… - Toxicology and applied …, 2018 - Elsevier
Due to many advantages Caenorhabditis elegans (C. elegans) has become a preferred
model of choice in many fields, including neurodevelopmental toxicity studies. This review …
model of choice in many fields, including neurodevelopmental toxicity studies. This review …
Oxidative stress, intestinal damage, and cell apoptosis: Toxicity induced by fluopyram in Caenorhabditis elegans
Fluopyram, a succinate dehydrogenase inhibitor fungicide and nematicide, has been used
extensively for agricultural pest control and toxicologically affects non-target organisms. In …
extensively for agricultural pest control and toxicologically affects non-target organisms. In …