Green chemistry in the synthesis of pharmaceuticals
The principles of green chemistry (GC) can be comprehensively implemented in green
synthesis of pharmaceuticals by choosing no solvents or green solvents (preferably water) …
synthesis of pharmaceuticals by choosing no solvents or green solvents (preferably water) …
3d transition metals for C–H activation
C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …
notable applications to material sciences, crop protection, drug discovery, and …
3d metallaelectrocatalysis for resource economical syntheses
P Gandeepan, LH Finger, TH Meyer… - Chemical Society …, 2020 - pubs.rsc.org
Resource economy constitutes one of the key challenges for researchers and practitioners
in academia and industries, in terms of rising demand for sustainable and green synthetic …
in academia and industries, in terms of rising demand for sustainable and green synthetic …
Resource economy by metallaelectrocatalysis: merging electrochemistry and CH activation
Oxidative CH activation has emerged as an increasingly powerful tool in molecular
syntheses. Despite major progress towards atom and step economy, these transformations …
syntheses. Despite major progress towards atom and step economy, these transformations …
Green strategies for transition metal-catalyzed C–H activation in molecular syntheses
Transition metal catalyzed C–H activation has surfaced as a powerful tool to improve the
efficacy of molecular synthesis. Last two decades have witnessed a considerable progress …
efficacy of molecular synthesis. Last two decades have witnessed a considerable progress …
C–H functionalization reactions under flow conditions
C–H functionalization technologies have progressed enormously in the last decade as
testified by the great number of publications that have appeared in the literature, which are …
testified by the great number of publications that have appeared in the literature, which are …
Cobalt‐Catalyzed Oxidative C− H Activation: Strategies and Concepts
Inexpensive cobalt‐catalyzed oxidative C− H functionalization has emerged as a powerful
tool for the construction of C− C and C− Het bonds, which offers unique potential for …
tool for the construction of C− C and C− Het bonds, which offers unique potential for …
Biomass-derived solvents for sustainable transition metal-catalyzed C–H activation
Transition metal-catalyzed C–H activation has emerged as an increasingly powerful strategy
in molecular syntheses and a particularly attractive alternative to classical methods of cross …
in molecular syntheses and a particularly attractive alternative to classical methods of cross …
Classic vs. C–H functionalization strategies in the synthesis of APIs: a sustainability comparison
The landscape of organic synthesis has changed in the last two decades, especially in
areas such as pharmaceutical synthesis and large-scale industrial synthesis. The progress …
areas such as pharmaceutical synthesis and large-scale industrial synthesis. The progress …
Allenes for versatile iron-catalyzed C–H activation by weak O-coordination: mechanistic insights by kinetics, intermediate isolation, and computation
AM Messinis, LH Finger, L Hu… - Journal of the American …, 2020 - ACS Publications
The iron-catalyzed hydroarylation of allenes was accomplished by weak phenone
assistance. The C–H activation proceeded with excellent efficacy and high ortho …
assistance. The C–H activation proceeded with excellent efficacy and high ortho …