Escherichia coli DNA replication: the old model organism still holds many surprises
K Łazowski, R Woodgate… - FEMS Microbiology …, 2024 - academic.oup.com
Research on Escherichia coli DNA replication paved the groundwork for many breakthrough
discoveries with important implications for our understanding of human molecular biology …
discoveries with important implications for our understanding of human molecular biology …
Systematic overexpression of genes encoded by mycobacteriophage Waterfoul reveals novel inhibitors of mycobacterial growth
D Heller, I Amaya, A Mohamed, I Ali, D Mavrodi… - G3, 2022 - academic.oup.com
Bacteriophages represent an enormous reservoir of novel genes, many of which are
unrelated to existing entries in public databases and cannot be assigned a predicted …
unrelated to existing entries in public databases and cannot be assigned a predicted …
Distal mutations in the β-clamp of DNA polymerase III* disrupt DNA orientation and affect exonuclease activity
MB Berger, GA Cisneros - Journal of the American Chemical …, 2023 - ACS Publications
DNA polymerases are responsible for the replication and repair of DNA found in all DNA-
based organisms. DNA Polymerase III is the main replicative polymerase of E. coli and is …
based organisms. DNA Polymerase III is the main replicative polymerase of E. coli and is …
During translesion synthesis, Escherichia coli DinB89 (T120P) alters interactions of DinB (Pol IV) with Pol III subunit assemblies and SSB, but not with the β clamp
MK Scotland, C Homiski, MD Sutton - Journal of Bacteriology, 2022 - Am Soc Microbiol
Translesion synthesis (TLS) by specialized DNA polymerases (Pols) is an evolutionarily
conserved mechanism for tolerating replication-blocking DNA lesions. Using the Escherichia …
conserved mechanism for tolerating replication-blocking DNA lesions. Using the Escherichia …
A bipartite interaction with the processivity clamp potentiates Pol IV-mediated TLS
S Chang, L Laureti, ES Thrall, MS Kay, G Philippin… - bioRxiv, 2024 - biorxiv.org
Processivity clamps mediate polymerase switching for translesion synthesis (TLS). All three
E. coli TLS polymerases interact with the beta processivity clamp through a conserved clamp …
E. coli TLS polymerases interact with the beta processivity clamp through a conserved clamp …
Elevated Levels of the Escherichia coli nrdAB-Encoded Ribonucleotide Reductase Counteract the Toxicity Caused by an Increased Abundance of the β Clamp
VMP Babu, C Homiski, MK Scotland… - Journal of …, 2021 - Am Soc Microbiol
Expression of the Escherichia coli dnaN-encoded β clamp at≥ 10-fold higher than
chromosomally expressed levels impedes growth by interfering with DNA replication. A …
chromosomally expressed levels impedes growth by interfering with DNA replication. A …