Ketamine, a racemic mixture consisting of (S)-and (R)-ketamine, has been in clinical use
since 1970. Although best characterized for its dissociative anesthetic properties, ketamine …

Background Ketamine was developed in the 1960s as a safer and more predictable
anesthetic than its precursor phencyclidine (PCP). It is a unique agent in procedural …

STUDY OBJECTIVE: We determine whether a 1: 1 mixture of ketamine and propofol (ketofol)
for emergency department (ED) procedural sedation results in a 13% or more absolute …

The use of a combination of ketamine and propofol (ketofol) for procedural sedation and
analgesia in the emergency department setting shows promise as an agent that may …

Objectives: This study evaluated the effectiveness, recovery time, and adverse event profile
of intravenous (IV) ketofol (mixed 1: 1 ketamine–propofol) for emergency department (ED) …

ACADEMIC EMERGENCY MEDICINE 2011; 18: 237–245© 2011 by the Society for
Academic Emergency Medicine Abstract Objectives: The objective was to evaluate the …

Background: The aim of this study was to compare the clinical efficacy and safety of propofol‐
ketamine with propofol‐fentanyl in pediatric patients undergoing diagnostic upper …

Objectives: The authors sought to compare the safety and efficacy of subdissociative‐dose
ketamine versus fentanyl as adjunct analgesics for emergency department (ED) procedural …

ACADEMIC EMERGENCY MEDICINE 2011; 18: 800–806© 2011 by the Society for
Academic Emergency Medicine Abstract Objectives: The authors performed a prospective …

BACKGROUND: Drugs such as propofol and ketamine are used alone or in combination to
provide sedation for medical procedures in children. The purpose of this systematic review …