Suboptimal nutrition is a leading cause of poor health. Nutrition and policy science have
advanced rapidly, creating confusion yet also providing powerful opportunities to reduce the …

Genome-wide association studies (GWAS) for BMI, waist-to-hip ratio, and other adiposity
traits have identified more than 300 single-nucleotide polymorphisms (SNPs). Although …

The specific metabolic contribution of consuming different energy-yielding macronutrients
(namely, carbohydrates, protein and lipids) to obesity is a matter of active debate. In this …

The rising prevalences of type 2 diabetes and obesity constitute major threats to human
health globally. Powerful social and economic factors influence the distribution of these …

The rapid rise of obesity during the past decades has coincided with a profound shift of our
living environment, including unhealthy dietary patterns, a sedentary lifestyle, and physical …

The liking and selective ingestion of palatable foods—including sweets—is biologically
controlled, and dysfunction of this regulation may promote unhealthy eating, obesity, and …

Physical activity (PA) may modify the genetic effects that give rise to increased risk of
obesity. To identify adiposity loci whose effects are modified by PA, we performed genome …

The worldwide obesity epidemic has been mainly attributed to lifestyle changes. However,
who becomes obese in an obesity-prone environment is largely determined by genetic …

The variation in weight within a shared environment is largely attributable to genetic factors.
Whilst many genes/loci confer susceptibility to obesity, little is known about the genetic …

Genetic studies have shown that obesity risk is heritable and that, of the many common
variants now associated with body mass index, those in an intron of the fat mass and obesity …