Natural products in the process of finding new drug candidates

P Vuorela, M Leinonen, P Saikku… - Current medicinal …, 2004 - ingentaconnect.com
Natural derived or originated compounds still play a major role as drugs, and as lead
structures for the development of synthetic molecules. About 50% of the drugs introduced to …

Natural product coumarins: biological and pharmacological perspectives

MI Hussain, QA Syed, MNK Khattak, B Hafez… - Biologia, 2019 - Springer
Plants produce and release a vast variety of secondary metabolites with diversified
functions, and possess ecological, toxicological and biological effects that mimic the …

[图书][B] Thin layer chromatography in phytochemistry

M Waksmundzka-Hajnos, J Sherma, T Kowalska - 2008 - taylorfrancis.com
Thin layer chromatography (TLC) is increasingly used in the fields of plant chemistry,
biochemistry, and molecular biology. Advantages such as speed, versatility, and low cost …

Natural medicine: the genus Angelica

SD Sarker, L Nahar - Current medicinal chemistry, 2004 - ingentaconnect.com
More than 60 species of medicinal plants belong to the genus Angelica (Family: Apiaceae).
Many of these species have long been used in ancient traditional medicine systems …

[PDF][PDF] Biological screening of plant coumarins

T Ojala - 2001 - Citeseer
Biological Screening of Plant Coumarins Page 1 Division of Pharmacognosy Department of
Pharmacy Faculty of Science University of Helsinki Biological Screening of Plant Coumarins …

Inhibitory effects of Angelica pubescens f. biserrata on 5-lipoxygenase and cyclooxygenase

JH Liu, S Zschocke, E Reininger, R Bauer - Planta Medica, 1998 - thieme-connect.com
Linoleic acid, osthol, osthenol and two polyacetylenes, falcarindiol and 11 (S), 16 (R)-
dihydroxyoctadeca-9Z, 17-diene-12, 14-diyn-1-yl acetate were found to be the most active …

Epilepsy in the Renaissance: a survey of remedies from 16th and 17th century German herbals

M Adams, SV Schneider, M Kluge, M Kessler… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Before modern anticonvulsive drugs were
developed people in central Europe used herbal remedies to treat epilepsy. Hundreds of …

A bioassay using Artemia salina for detecting phototoxicity of plant coumarins

T Ojala, P Vuorela, J Kiviranta, H Vuorela… - Planta …, 1999 - thieme-connect.com
Artemia salina (brine shrimp) has been successfully used for toxicity testing, and a screening
test for phototoxicity has been developed based on this method. The ability of the method to …

Oxypeucedanin: Chemotaxonomy, isolation, and bioactivities

J Mottaghipisheh - Plants, 2021 - mdpi.com
The present review comprehensively gathered phytochemical, bioactivity, and
pharmacokinetic reports on a linear furanocoumarin, namely oxypeucedanin …

Bioactivity-Guided Fractionation for the Butyrylcholinesterase Inhibitory Activity of Furanocoumarins from Angelica archangelica L. Roots and Fruits

N Wszelaki, K Paradowska, MK Jamróz… - Journal of agricultural …, 2011 - ACS Publications
Isolation and identification of the inhibitors of butyrylcholinesterase (BChE), obtained from
the extracts of roots and fruits of Angelica archangelica L., are reported. Our results …