Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Nanomaterials and nanomaterials-based drug delivery to promote cutaneous wound healing

T Liu, Y Lu, R Zhan, W Qian, G Luo - Advanced Drug Delivery Reviews, 2023 - Elsevier
Various factors could damage the structure and integrity of skin to cause wounds.
Nonhealing or chronic wounds seriously affect the well-being of patients and bring heavy …

Senescence in wound repair: emerging strategies to target chronic healing wounds

HN Wilkinson, MJ Hardman - Frontiers in cell and developmental …, 2020 - frontiersin.org
Cellular senescence is a fundamental stress response that restrains tumour formation. Yet,
senescence cells are also present in non-cancerous states, accumulating exponentially with …

[HTML][HTML] Research status of biodegradable metals designed for oral and maxillofacial applications: A review

D Xia, F Yang, Y Zheng, Y Liu, Y Zhou - Bioactive materials, 2021 - Elsevier
The oral and maxillofacial regions have complex anatomical structures and different tissue
types, which have vital health and aesthetic functions. Biodegradable metals (BMs) is a …

Macrophage polarization in THP-1 cell line and primary monocytes: A systematic review

ZNM Yasin, FNM Idrus, CH Hoe, GB Yvonne-Tee - Differentiation, 2022 - Elsevier
Macrophages derived from human monocytic leukemia THP-1 cell line are often used as the
alternative of human primary macrophage. However, the polarization method of THP-1 to …

Ironing out the details: how iron orchestrates macrophage polarization

Y Xia, Y Li, X Wu, Q Zhang, S Chen, X Ma… - Frontiers in …, 2021 - frontiersin.org
Iron fine-tunes innate immune responses, including macrophage inflammation. In this
review, we summarize the current understanding about the iron in dictating macrophage …

Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages

CS Nascimento, ÉAR Alves, CP de Melo… - …, 2021 - Taylor & Francis
Cancer immunotherapy is the most promising trend in oncology, focusing on helping or
activating the patient's immune system to identify and fight against cancer. In the last …

Effects of RGD-grafted phosphatidylserine-containing liposomes on the polarization of macrophages and bone tissue regeneration

L Wu, Y Kim, GM Seon, SH Choi, HC Park, G Son… - Biomaterials, 2021 - Elsevier
Phosphatidylserine-containing liposomes (PSLs) can mimic the anti-inflammatory effects of
apoptotic cells by binding to the phosphatidylserine receptors of macrophages. MGF-E8, a …

Cellular senescence in acute and chronic wound repair

HN Wilkinson, MJ Hardman - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
Cellular senescence, once thought an artifact of in vitro culture or passive outcome of aging,
has emerged as fundamental to tissue development and function. The senescence …

[HTML][HTML] Improving hard metal implant and soft tissue integration by modulating the “inflammatory-fibrous complex” response

P Huang, J Xu, L Xie, G Gao, S Chen, Z Gong, X Lao… - Bioactive Materials, 2023 - Elsevier
Soft tissue integration is one major difficulty in the wide applications of metal materials in soft
tissue-related areas. The inevitable inflammatory response and subsequent fibrous reaction …