Childhood maltreatment is the most important preventable risk factor for psychiatric
disorders. Maltreated individuals typically develop psychiatric disorders at an earlier age …

Abstract Background The Center for Disease Control (CDC) and Kaiser Permanente
developed the Adverse Childhood Experiences (ACE) scale to identify negative experiences …

The term “toxic stress” refers to a wide array of biological changes that occur at the
molecular, cellular, and behavioral levels when there is prolonged or significant adversity in …

Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …

Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …

Children who have been exposed to maltreatment and other adverse childhood experiences
(ACEs) are at increased risk for various negative adult health outcomes, including cancer …

Abstract Objective. In 1998, Felitti and colleagues published the first study of the Adverse
Childhood Experiences-Questionnaire (ACE-Q), a 10-item scale used to correlate childhood …

This study examined the association of adverse childhood experiences (ACEs) with early-
onset chronic conditions. We analyzed data from the 2011–2012 Behavioral Risk Factor …

Background The relative health and robustness of a field of research can be approximated
by assessing peer reviewed journal publication trends for articles pertinent to the field. To …

Objective Childhood maltreatment increases risk for psychopathology. For some highly
prevalent disorders (major depression, substance abuse, anxiety disorders, and …