Over the past 10 years, the development and convergence of microbial opsin engineering,
modular genetic methods for cell-type targeting and optical strategies for guiding light …

The brain operates through the synaptic interaction of distant neurons within flexible, often
heterogeneous, distributed systems. Histological studies have detailed the connections …

Mounting evidence suggests that neuronal activity influences myelination, potentially
allowing for experience-driven modulation of neural circuitry. The degree to which neuronal …

The activity of neuronal circuits of the neocortex underlies our ability to perceive the world
and interact with our environment. During development, these circuits emerge from dynamic …

The time that it takes the brain to develop is highly variable across animals. Although staging
systems equate major developmental milestones between mammalian species, it remains …

The corpus callosum (CC) connects the cerebral hemispheres and is the major mammalian
commissural tract. It facilitates bilateral sensory integration and higher cognitive functions …

Axonal connections between the left and right sides of the brain are crucial for bilateral
integration of lateralized sensory, motor, and associative functions. Throughout vertebrate …

Perinatal white matter injury (WMI) is the most common brain injury in premature infants and
can lead to life-long neurological deficits such as cerebral palsy. Preterm birth is typically …

Dysfunction of gamma-aminobutyric acid (GABA) ergic circuits is strongly associated with
neurodevelopmental disorders. However, it is unclear how genetic predispositions impact …

Calcium influx can be stimulated by various intra-and extracellular signals to set coordinated
gene expression programs into motion. As such, the precise regulation of intracellular …