CCDC144NL-AS1/hsa-miR-143-3p/HMGA2 interaction: In-silico and clinically implicated in CRC progression, correlated to tumor stage and size in case-controlled …

YK Abd El Fattah, AI Abulsoud, SG AbdelHamid… - International Journal of …, 2023 - Elsevier
Unravel the regulatory mechanism of lncRNA CCDC144NL-AS1 in CRC hsa-miR-143-3p,
downstream protein HMGA2 interaction arm, association with clinicopathological …

Contribution of CRNDE lncRNA in the development of cancer and the underlying mechanisms

S Ghafouri-Fard, A Safarzadeh, BM Hussen… - … -Research and Practice, 2023 - Elsevier
Abstract Colorectal Neoplasia Differentially Expressed (CRNDE) is an lncRNA with crucial
roles in cancer development. It is located on chromosome 16 on the opposite strand to the …

[HTML][HTML] Exosomal non-coding RNAs: blueprint in colorectal cancer metastasis and therapeutic targets

BM Hussen, ST Abdullah, SR Abdullah… - Non-coding RNA …, 2023 - Elsevier
Colorectal cancer (CRC) is ranked as the world's third-most prevalent cancer, and metastatic
CRC considerably increases cancer-related fatalities globally. A number of complex …

[HTML][HTML] Cancer-associated fibroblasts-derived extracellular vesicles carrying lncRNA SNHG3 facilitate colorectal cancer cell proliferation via the miR-34b-5p/HuR …

J Zhao, H Lin, K Huang, S Li - Cell Death Discovery, 2022 - nature.com
Abstract Cancer-associated fibroblasts (CAFs)-derived extracellular vesicles (EVs) can
mediate tumorigenesis. Long noncoding RNA (LncRNA) SNHG3 is implicated in colorectal …

[HTML][HTML] Identification of diagnostic biomarkers via weighted correlation network analysis in colorectal cancer using a system biology approach

S Ghafouri-Fard, A Safarzadeh, M Taheri, E Jamali - Scientific Reports, 2023 - nature.com
Colorectal cancer (CRC) is the third most frequent cancer to be diagnosed in both females
and males necessitating identification of effective biomarkers. An in-silico system biology …

Revealing the role of serum exosomal novel long non-coding RNA NAMPT-AS as a promising diagnostic/prognostic biomarker in colorectal cancer patients

NI Rizk, DH Kassem, AI Abulsoud, S AbdelHalim… - Life Sciences, 2024 - Elsevier
Aims Colorectal cancer (CRC) is the second leading cause of cancer-related deaths
worldwide. Nicotinamide phosphoribosyl-transferase (NAMPT) was found to be over …

LncRNA OTUD6B-AS1 overexpression promoted GPX4-mediated ferroptosis to suppress radioresistance in colorectal cancer

Z Zhang, B Ye, Y Lin, W Liu, J Deng, W Ji - Clinical and Translational …, 2023 - Springer
Background Radiotherapy is widely employed in colorectal cancer (CRC) treatment but is
often compromised by developed radioresistance. This study explored the mechanism of …

[HTML][HTML] Peptide encoded by lncRNA BVES-AS1 promotes cell viability, migration, and invasion in colorectal cancer cells via the SRC/mTOR signaling pathway

W Zheng, Y Guo, G Zhang, J Bai, Y Song, X Song… - Plos one, 2023 - journals.plos.org
Long non-coding RNAs (lncRNAs) have been revealed to harbor open reading frames
(ORFs) that can be translated into small peptides. The peptides may participate in the …

[HTML][HTML] LncRNA LOC105369504 inhibits tumor proliferation and metastasis in colorectal cancer by regulating PSPC1

T Zhan, X Cheng, Q Zhu, Z Han, K Zhu, J Tan… - Cell Death …, 2023 - nature.com
There is growing evidence that long non-coding RNAs (lncRNAs) are significant contributors
to the epigenetic mechanisms implicated in the emergence, progression and metastasis of …

[HTML][HTML] A pan-cancer analysis indicates long noncoding RNA HAND2-AS1 as a potential prognostic, immunomodulatory and therapeutic biomarker in various …

P Samadi, M Shahnazari, A Shekari, F Maghool… - Cancer Cell …, 2023 - Springer
Abstract The HAND2-AS1 (HAND2 Antisense RNA 1) Long noncoding RNA (lncRNA) has
emerged as a participant in the initiation of various cancer types, underscoring its pivotal …