[HTML][HTML] Polycystic ovary syndrome in insulin-resistant adolescents with obesity: the role of nutrition therapy and food supplements as a strategy to protect fertility

V Calcaterra, E Verduci, H Cena, VC Magenes… - Nutrients, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in young
reproductive-aged women. PCOS is often associated with obesity and impairs reproductive …

Inositols: from established knowledge to novel approaches

S Dinicola, V Unfer, F Facchinetti, CO Soulage… - International Journal of …, 2021 - mdpi.com
Myo-inositol (myo-Ins) and D-chiro-inositol (D-chiro-Ins) are natural compounds involved in
many biological pathways. Since the discovery of their involvement in endocrine signal …

Myo-Inositol and Its Derivatives: Their Emerging Role in the Treatment of Human Diseases

DR Chhetri - Frontiers in pharmacology, 2019 - frontiersin.org
Myo-inositol has been established as an important growth-promoting factor of mammalian
cells and animals. The role of myo-inositol as a lipotropic factor has been proven, in addition …

Antioxidants for female subfertility

MG Showell, R Mackenzie-Proctor… - … of systematic reviews, 2020 - cochranelibrary.com
Background A couple may be considered to have fertility problems if they have been trying
to conceive for over a year with no success. This may affect up to a quarter of all couples …

Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility

LC Morley, T Tang, E Yasmin… - Cochrane Database …, 2017 - cochranelibrary.com
Background Polycystic ovary syndrome (PCOS) is characterised by infrequent or absent
ovulation, and high levels of androgens and insulin (hyperinsulinaemia). Hyperinsulinaemia …

Fertility-sparing approach in women affected by stage I and low-grade endometrial carcinoma: an updated overview

G Gullo, A Etrusco, G Cucinella, A Perino… - International Journal of …, 2021 - mdpi.com
Endometrial cancer (EC) is a deleterious condition which strongly affects a woman's quality
of life. Although aggressive interventions should be considered to treat high-grade EC, a …

Myo-inositol in assisted reproductive technology from bench to bedside

A Etrusco, AS Laganà, V Chiantera… - Trends in Endocrinology …, 2024 - cell.com
Inositols are insulin-sensitizing compounds of promising efficacy in the management of
polycystic ovary syndrome (PCOS). On the one hand, myo-inositol (myo-ins) plays a …

The use of D-chiro-Inositol in clinical practice

R Gambioli, G Forte, C Aragona… - European Review for …, 2021 - iris.uniroma1.it
OBJECTIVE: D-chiro-Inositol has been widely used in clinical practice to induce ovulation in
women with polycystic ovary syndrome. Only recent evidence established that this molecule …

The “Other” Inositols and Their Phosphates: Synthesis, Biology, and Medicine (with Recent Advances in myo‐Inositol Chemistry)

MP Thomas, SJ Mills, BVL Potter - … Chemie International Edition, 2016 - Wiley Online Library
Cell signaling via inositol phosphates, in particular via the second messenger myo‐inositol
1, 4, 5‐trisphosphate, and phosphoinositides comprises a huge field of biology. Of the nine …

[PDF][PDF] The combined therapy with myo-inositol and D-chiro-inositol reduces the risk of metabolic disease in PCOS overweight patients compared to myo-inositol …

M Nordio, E Proietti - Eur Rev Med Pharmacol Sci, 2012 - inositolgroup.com
Aim: In this study, we aim to verify whether the two molecules have a synergistic action by
acting on their specific cellular pathways. The effectiveness in reducing the risk of metabolic …