Anthropometric and adiposity indicators and risk of type 2 diabetes: systematic review and dose-response meta-analysis of cohort studies

A Jayedi, S Soltani, SZ Motlagh, A Emadi, H Shahinfar… - Bmj, 2022 - bmj.com
Objective To present a comprehensive review of the association between measures of body
weight, waist, and fat, and different ratios of these measures, and the risk of type 2 diabetes …

[HTML][HTML] Iron metabolism and ferroptosis in type 2 diabetes mellitus and complications: mechanisms and therapeutic opportunities

R Miao, X Fang, Y Zhang, J Wei, Y Zhang… - Cell Death & Disease, 2023 - nature.com
The maintenance of iron homeostasis is essential for proper endocrine function. A growing
body of evidence suggests that iron imbalance is a key factor in the development of several …

[HTML][HTML] The role of ferroptosis in diabetic cardiovascular diseases and the intervention of active ingredients of traditional Chinese medicine

X Zhang, J Sun, J Wang, T Meng, J Yang… - Frontiers in …, 2023 - frontiersin.org
Cardiovascular diseases (CVDs), encompassing ischaemic heart disease, cardiomyopathy,
and heart failure, among others, are the most prevalent complications of diabetes and the …

[HTML][HTML] Targeting ferroptosis with miR-144-3p to attenuate pancreatic β cells dysfunction via regulating USP22/SIRT1 in type 2 diabetes

S Zhang, X Liu, J Wang, F Yuan, Y Liu - Diabetology & Metabolic …, 2022 - Springer
Background Recently, ferroptosis has been implicated in the pathologic process of several
diseases including type 2 diabetes mellitus (T2DM). However, molecular mechanisms …

Erythropoietin ameliorates cognitive dysfunction in mice with type 2 diabetes mellitus via inhibiting iron overload and ferroptosis

T Guo, Y Yu, W Yan, M Zhang, X Yi, N Liu, X Cui… - Experimental …, 2023 - Elsevier
Type 2 diabetes mellitus (T2DM) is strongly associated with an increased risk of developing
cognitive dysfunction. Numerous studies have indicated that erythropoietin (EPO) has …

Exploring Lactoferrin as a novel marker for disease pathology and ferroptosis regulation in gestational diabetes

S Mohandas, KL Milan, M Anuradha… - Journal of Reproductive …, 2024 - Elsevier
Iron overload is linked to heightened susceptibility to ferroptosis, a process increasingly
implicated in diabetes pathogenesis. This present study aims to assess the utility of …

[HTML][HTML] Association between systemic iron status and β-cell function and insulin sensitivity in patients with newly diagnosed type 2 diabetes

Y Qin, Y Huang, Y Li, L Qin, Q Wei, X Chen… - Frontiers in …, 2023 - frontiersin.org
Objective Abnormal iron metabolism is related to the risk of diabetes, but the underlying
mechanism of this association remains uncertain. This study was conducted to evaluate the …

Exposure to multiple metals and diabetes mellitus risk in dong ethnicity in China: from the China multi-ethnic cohort study

Q Yang, Y Liu, L Liu, L Zhang, J Lei, Q Wang… - Environmental …, 2023 - Springer
Metals play an important role in the development of diabetes mellitus (DM). The association
of metals with diabetes among the Dong ethnicity in China remains poorly understood. The …

[HTML][HTML] Correlations between iron status and body composition in patients with type 2 diabetes mellitus

C Zimiao, L Dongdong, C Shuoping, Z Peng… - Frontiers in …, 2022 - frontiersin.org
Background Our study aimed to investigate the association between iron metabolism and
body composition in patients with type 2 diabetes mellitus (T2DM). Methods A total of 824 …

The complementary roles of iron and estrogen in menopausal differences in cardiometabolic outcomes

NS Ahanchi, F Khatami, E Llanaj, HG Quezada-Pinedo… - Clinical Nutrition, 2024 - Elsevier
Biological hormonal changes are frequently cited as an explanatory factor of sex and
menopause differences in cardiometabolic diseases (CMD) and its associated risk factors …