Background Current diagnostic criteria for hypoxic–ischemic encephalopathy in the early
hours lack objective measurement tools. Therefore, this systematic review aims to identify …

Hypoxic–ischemic encephalopathy is one of the leading causes of death and neurological
disability worldwide. A key issue in neonates with hypoxic–ischemic encephalopathy is …

Background Inflammation plays a crucial role in the pathogenesis of hypoxic–ischemic
encephalopathy (HIE). The aim of this study was to measure inflammation in HIE through an …

Toll-like receptors (TLR) are one of the main constituents of the innate immune system in
mammals. They can detect conserved microbial structures (pathogen-associated molecular …

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In this study, the expression of the genes of the amyloid protein precursor, β-secretase,
presenilin 1 and 2 by RT-PCR in the lymphocytes of newborns after perinatal asphyxia and …

La hipotermia terapéutica (HT) es el tratamiento estándar de la Encefalopatía Hipóxico-
Isquémica (EHI) neonatal desde hace más de una década. Esta terapia ha sido uno de los …

Perinatal asphyxia (PA) poses a significant risk of hypoxic–ischemic encephalopathy (HIE),
affecting up to 8 per 1000 live births, leading to brain injury due to inadequate oxygen and …

We congratulate Balada et al. 1 for pursuing important transcriptomic research in neonatal
encephalopathy (NE). They examined the messenger RNA (mRNA) expression of 23 …

The comment by Burgod et al., 1 for which we are grateful, encompasses invaluable insights
on the use of gene expression as a disease stratification tool in neonatal encephalopathy …