Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen
Virus host shifts are generally associated with novel adaptations to exploit the cells of the
new host species optimally. Surprisingly, Severe Acute Respiratory Syndrome Coronavirus …
new host species optimally. Surprisingly, Severe Acute Respiratory Syndrome Coronavirus …
Codon usage provides insights into the adaptive evolution of mycoviruses in their associated fungi host
Q Wang, X Lyu, J Cheng, Y Fu, Y Lin… - International Journal of …, 2022 - mdpi.com
Codon usage bias (CUB) could reflect co-evolutionary changes between viruses and hosts
in contrast to plant and animal viruses, and the systematic analysis of codon usage among …
in contrast to plant and animal viruses, and the systematic analysis of codon usage among …
Significant non-existence of sequences in genomes and proteomes
G Koulouras, MC Frith - Nucleic acids research, 2021 - academic.oup.com
Minimal absent words (MAWs) are minimal-length oligomers absent from a genome or
proteome. Although some artificially synthesized MAWs have deleterious effects, there is still …
proteome. Although some artificially synthesized MAWs have deleterious effects, there is still …
Natural selection in the evolution of SARS-CoV-2 in bats, not humans, created a highly capable human pathogen
RNA viruses are proficient at switching host species, and evolving adaptations to exploit the
new host's cells efficiently. Surprisingly, SARS-CoV-2 has apparently required no significant …
new host's cells efficiently. Surprisingly, SARS-CoV-2 has apparently required no significant …
Evidence of significant natural selection in the evolution of SARS-CoV-2 in bats, not humans
OA MacLean, S Lytras, JB Singer… - COVID-19 …, 2020 - scholarshare.temple.edu
RNA viruses are proficient at switching to novel host species due to their fast mutation rates.
Implicit in this assumption is the need to evolve adaptations in the new host species to …
Implicit in this assumption is the need to evolve adaptations in the new host species to …
Investigating the diversity and host range of novel parvoviruses from North American ducks using epidemiology, phylogenetics, genome structure, and codon usage …
Parvoviruses are small single-stranded DNA viruses that can infect both vertebrates and
invertebrates. We report here the full characterization of novel viruses we identified in ducks …
invertebrates. We report here the full characterization of novel viruses we identified in ducks …
Insights into the evolutionary forces that shape the codon usage in the viral genome segments encoding intrinsically disordered protein regions
Intrinsically disordered regions/proteins (IDRs) are abundant across all the domains of life,
where they perform important regulatory roles and supplement the biological functions of …
where they perform important regulatory roles and supplement the biological functions of …
Codon usage bias and dinucleotide preference in 29 Drosophila species
Codon usage bias, where certain codons are used more frequently than their synonymous
counterparts, is an interesting phenomenon influenced by three evolutionary forces …
counterparts, is an interesting phenomenon influenced by three evolutionary forces …
Intra-genomic heterogeneity in CpG dinucleotide composition in dengue virus
Purpose Dengue virus is a life-threatening virus and cases of dengue infection have been
increasing steadily in the past decades causing millions of deaths every year. So far, there is …
increasing steadily in the past decades causing millions of deaths every year. So far, there is …
Analysis of codon usage bias in potato virus Y non-recombinant strains
MM Gómez, E de Mello Volotão, IR Assandri, M Peyrou… - Virus research, 2020 - Elsevier
Potato virus Y (PVY) is a member of the genus Potyvirus, family Potyviridae, is considered
one of the most devastating pest affecting economically important crops, such as potato …
one of the most devastating pest affecting economically important crops, such as potato …