Plants as antimalarial agents in Sub-Saharan Africa

KC Chinsembu - Acta tropica, 2015 - Elsevier
Although the burden of malaria is decreasing, parasite resistance to current antimalarial
drugs and resistance to insecticides by vector mosquitoes threaten the prospects of malaria …

Pathogens in space: Advancing understanding of pathogen dynamics and disease ecology through landscape genetics

CP Kozakiewicz, CP Burridge, WC Funk… - Evolutionary …, 2018 - Wiley Online Library
Landscape genetics has provided many insights into how heterogeneous landscape
features drive processes influencing spatial genetic variation in free‐living organisms. This …

Drug-Resistance and Population Structure of Plasmodium falciparum Across the Democratic Republic of Congo Using High-Throughput Molecular Inversion Probes

O Aydemir, M Janko, NJ Hathaway… - The Journal of …, 2018 - academic.oup.com
A better understanding of the drivers of the spread of malaria parasites and drug resistance
across space and time is needed. These drivers can be elucidated using genetic tools. Here …

The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC

R Verity, O Aydemir, NF Brazeau, OJ Watson… - Nature …, 2020 - nature.com
Abstract The Democratic Republic of the Congo (DRC) harbors 11% of global malaria
cases, yet little is known about the spatial and genetic structure of the parasite population in …

A scoping review of spatial analysis approaches using health survey data in sub-Saharan Africa

S Manda, N Haushona, R Bergquist - International journal of …, 2020 - mdpi.com
Spatial analysis has become an increasingly used analytic approach to describe and
analyze spatial characteristics of disease burden, but the depth and coverage of its usage …

A deep sequencing approach to estimate Plasmodium falciparum complexity of infection (COI) and explore apical membrane antigen 1 diversity

RH Miller, NJ Hathaway, O Kharabora… - Malaria journal, 2017 - Springer
Background Humans living in regions with high falciparum malaria transmission intensity
harbour multi-strain infections comprised of several genetically distinct malaria haplotypes …

The changing landscape of Plasmodium falciparum drug resistance in the Democratic Republic of Congo

M Deutsch-Feldman, O Aydemir, M Carrel… - BMC infectious …, 2019 - Springer
Background Drug resistant malaria is a growing concern in the Democratic Republic of the
Congo (DRC), where previous studies indicate that parasites resistant to sulfadoxine …

Genetic structure of Spirometra mansoni (Cestoda: Diphyllobothriidae) populations in China revealed by a Target SSR-seq method

FF Xu, WQ Chen, W Liu, SS Liu, YX Wang, J Chen… - Parasites & …, 2022 - Springer
Abstract Background In China, the plerocercoid of the cestode Spirometra mansoni is the
main causative agent of human and animal sparganosis. However, the population genetic …

High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya

CS Nelson, KM Sumner, E Freedman… - Nature …, 2019 - nature.com
Novel interventions that leverage the heterogeneity of parasite transmission are needed to
achieve malaria elimination. To better understand spatial and temporal dynamics of …

Modeling impact and cost‐effectiveness of driving‐Y gene drives for malaria elimination in the Democratic Republic of the Congo

N Metchanun, C Borgemeister, G Amzati… - Evolutionary …, 2022 - Wiley Online Library
Malaria elimination will be challenging in countries that currently continue to bear high
malaria burden. Sex‐ratio‐distorting gene drives, such as driving‐Y, could play a role in an …