Lyme borreliosis

AC Steere, F Strle, GP Wormser, LT Hu… - Nature reviews Disease …, 2016 - nature.com
Lyme borreliosis is a tick-borne disease that predominantly occurs in temperate regions of
the northern hemisphere and is primarily caused by the bacterium Borrelia burgdorferi in …

Interactions between Borrelia burgdorferi and ticks

C Kurokawa, GE Lynn, JHF Pedra, U Pal… - Nature Reviews …, 2020 - nature.com
Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

Large-scale comparative analyses of tick genomes elucidate their genetic diversity and vector capacities

N Jia, J Wang, W Shi, L Du, Y Sun, W Zhan, JF Jiang… - Cell, 2020 - cell.com
Among arthropod vectors, ticks transmit the most diverse human and animal pathogens,
leading to an increasing number of new challenges worldwide. Here we sequenced and …

Tick-pathogen interactions and vector competence: identification of molecular drivers for tick-borne diseases

J De la Fuente, S Antunes, S Bonnet… - Frontiers in cellular …, 2017 - frontiersin.org
Ticks and the pathogens they transmit constitute a growing burden for human and animal
health worldwide. Vector competence is a component of vectorial capacity and depends on …

Lyme disease in humans

JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

The essential role of tick salivary glands and saliva in tick feeding and pathogen transmission

L Šimo, M Kazimirova, J Richardson… - Frontiers in cellular and …, 2017 - frontiersin.org
As long-term pool feeders, ticks have developed myriad strategies to remain discreetly but
solidly attached to their hosts for the duration of their blood meal. The critical biological …

The role of ticks in the maintenance and transmission of Crimean-Congo hemorrhagic fever virus: A review of published field and laboratory studies

A Gargili, A Estrada-Peña, JR Spengler, A Lukashev… - Antiviral research, 2017 - Elsevier
This manuscript is part of a series of reviews that aim to cover published research on
Crimean-Congo hemorrhagic fever (CCHF) and its etiological agent, CCHF virus (CCHFV) …

Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

JD Radolf, MJ Caimano, B Stevenson… - Nature reviews …, 2012 - nature.com
In little more than 30 years, Lyme disease, which is caused by the spirochaete Borrelia
burgdorferi, has risen from relative obscurity to become a global public health problem and a …

The ecology of ticks and epidemiology of tick-borne viral diseases

A Estrada-Peña, J de la Fuente - Antiviral research, 2014 - Elsevier
A number of tick-borne diseases of humans have increased in incidence and geographic
range over the past few decades, and there is concern that they will pose an even greater …

Gut microbiota of the tick vector Ixodes scapularis modulate colonization of the Lyme disease spirochete

S Narasimhan, N Rajeevan, L Liu, YO Zhao, J Heisig… - Cell host & …, 2014 - cell.com
Arthopods such as Ixodes scapularis ticks serve as vectors for many human pathogens. The
arthropod gut presents a pivotal microbial entry point and determines pathogen colonization …