Health professionals are encouraged to take the Guidelines fully into account when
exercising their clinical judgment, as well as in the determination and the implementation of …

Diabetes mellitus bezeichnet eine Gruppe von heterogenen Erkrankungen, deren
gemeinsamer Befund die Erhöhung der Blutglukosekonzentration ist. Die gegenwärtige …

Клинические рекомендации уже давно вошли в число рабочих инструментов
современного врача, помогая ему быстро ориентироваться в наиболее эффективных …

Background Blood pressure lowering is an established strategy for preventing microvascular
and macrovascular complications of diabetes, but its role in the prevention of diabetes itself …

Metabolic syndrome is defined by a constellation of interconnected physiological,
biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular …

Complex and bidirectional interactions between the renin–angiotensin system (RAS) and
autonomic nervous system have been well established for cardiovascular regulation under …

Background Essential arterial hypertension is one of the main treatable cardiovascular risk
factors. In Germany, approximately 13% of women and 18% of men have uncontrolled high …

GRADE suggests that examination of 95% confidence intervals (CIs) provides the optimal
primary approach to decisions regarding imprecision. For practice guidelines, rating down …

Resistant hypertension (RHTN) is defined as uncontrolled blood pressure despite the use
of≥ 3 antihypertensive agents of different classes, including a diuretic, usually thiazide-like …

Recommendations about therapy for hypertension are here preceded by some
considerations on the strength of available evidence on the benefits associated with …